BDBM50097523 CHEMBL3586071

SMILES: CNC(=O)c1cc(ccn1)-c1ccc(NC(=O)Nc2ccc(Cl)c(c2)C(F)(F)F)cc1

InChI Key: InChIKey=BAATUFDCYJAHSD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50097523   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50097523 (CHEMBL3586071) Show SMILES CNC(=O)c1cc(ccn1)-c1ccc(NC(=O)Nc2ccc(Cl)c(c2)C(F)(F)F)cc1 Show InChI InChI=1S/C21H16ClF3N4O2/c1-26-19(30)18-10-13(8-9-27-18)12-2-4-14(5-3-12)28-20(31)29-15-6-7-17(22)16(11-15)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a	n/a
Xi'an Jiaotong University Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 (unknown origin) after 1 hr by ADP-Glo assay				Bioorg Med Chem 23: 3228-36 (2015) Article DOI: 10.1016/j.bmc.2015.04.071 BindingDB Entry DOI: 10.7270/Q2CV4KGG
					More data for this Ligand-Target Pair