BDBM50097565 CHEMBL3589947

SMILES: COc1ccc(NC(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)NCC2(CCCCC2)c2ccnc(F)c2)cc1

InChI Key: InChIKey=IWQPJAADIUVKSH-UHFFFAOYSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50097565   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM50097565 (CHEMBL3589947) Show SMILES COc1ccc(NC(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)NCC2(CCCCC2)c2ccnc(F)c2)cc1 |r| Show InChI InChI=1S/C19H21N3O3/c1-3-4-12-25-15-10-11-20-17-16(15)18(23)22(19(24)21(17)2)13-14-8-6-5-7-9-14/h5-11H,3-4,12-13H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	660	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari 'Aldo Moro' Curated by ChEMBL					Assay Description Agonist activity at FPR2 in human PMN assessed as stimulation of Ca2+ influx measured every 5 secs for 240 secs by FLIPR assay in presence of probene...				Bioorg Med Chem 23: 3913-24 (2015) Article DOI: 10.1016/j.bmc.2014.12.007 BindingDB Entry DOI: 10.7270/Q2MS3VHB
					More data for this Ligand-Target Pair
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM50097565 (CHEMBL3589947) Show SMILES COc1ccc(NC(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)NCC2(CCCCC2)c2ccnc(F)c2)cc1 |r| Show InChI InChI=1S/C19H21N3O3/c1-3-4-12-25-15-10-11-20-17-16(15)18(23)22(19(24)21(17)2)13-14-8-6-5-7-9-14/h5-11H,3-4,12-13H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari 'Aldo Moro' Curated by ChEMBL					Assay Description Agonist activity at FPR2 in human PMN assessed as stimulation of Ca2+ influx measured every 5 secs for 240 secs by FLIPR assay in absence of probenec...				Bioorg Med Chem 23: 3913-24 (2015) Article DOI: 10.1016/j.bmc.2014.12.007 BindingDB Entry DOI: 10.7270/Q2MS3VHB
					More data for this Ligand-Target Pair
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM50097565 (CHEMBL3589947) Show SMILES COc1ccc(NC(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)NCC2(CCCCC2)c2ccnc(F)c2)cc1 |r| Show InChI InChI=1S/C19H21N3O3/c1-3-4-12-25-15-10-11-20-17-16(15)18(23)22(19(24)21(17)2)13-14-8-6-5-7-9-14/h5-11H,3-4,12-13H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari 'Aldo Moro' Curated by ChEMBL					Assay Description Agonist activity at human FPR2 transfected in human HL60 cells assessed as stimulation of Ca2+ influx measured every 5 secs for 240 secs by FLIPR ass...				Bioorg Med Chem 23: 3913-24 (2015) Article DOI: 10.1016/j.bmc.2014.12.007 BindingDB Entry DOI: 10.7270/Q2MS3VHB
					More data for this Ligand-Target Pair
Formyl peptide receptor-related sequence 1 (Mus musculus)	BDBM50097565 (CHEMBL3589947) Show SMILES COc1ccc(NC(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)NCC2(CCCCC2)c2ccnc(F)c2)cc1 |r| Show InChI InChI=1S/C19H21N3O3/c1-3-4-12-25-15-10-11-20-17-16(15)18(23)22(19(24)21(17)2)13-14-8-6-5-7-9-14/h5-11H,3-4,12-13H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari 'Aldo Moro' Curated by ChEMBL					Assay Description Agonist activity at FPR2 in BALB/c mouse assessed as stimulation of Ca2+ influx measured every 5 secs for 240 secs by FLIPR assay				Bioorg Med Chem 23: 3913-24 (2015) Article DOI: 10.1016/j.bmc.2014.12.007 BindingDB Entry DOI: 10.7270/Q2MS3VHB
					More data for this Ligand-Target Pair