BDBM50097572 6-Chloro-4-(1-hydroxy-cyclopropylethynyl)-4-trifluoromethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one::CHEMBL155936

SMILES: OC1(CC1)C#CC1(OC(=O)Nc2ccc(Cl)cc12)C(F)(F)F

InChI Key: InChIKey=BHOCYCABHGMRFS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50097572   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50097572 (6-Chloro-4-(1-hydroxy-cyclopropylethynyl)-4-triflu...) Show SMILES OC1(CC1)C#CC1(OC(=O)Nc2ccc(Cl)cc12)C(F)(F)F Show InChI InChI=1S/C14H9ClF3NO3/c15-8-1-2-10-9(7-8)13(14(16,17)18,22-11(20)19-10)6-5-12(21)3-4-12/h1-2,7,21H,3-4H2,(H,19,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 reverse transcriptase				Bioorg Med Chem Lett 11: 619-22 (2001) BindingDB Entry DOI: 10.7270/Q2BC403C
					More data for this Ligand-Target Pair