BDBM50097608 3-(4-Chloro-phenyl)-5-((S)-1-methyl-pyrrolidin-2-ylmethoxy)-pyridine::CHEMBL157188

SMILES: CN1CCC[C@H]1COc1cncc(c1)-c1ccc(Cl)cc1

InChI Key: InChIKey=RWJMDBDHEUCWHN-INIZCTEOSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50097608   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit (Rattus norvegicus (Rat))	BDBM50097608 (3-(4-Chloro-phenyl)-5-((S)-1-methyl-pyrrolidin-2-y...) Show SMILES CN1CCC[C@H]1COc1cncc(c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C17H19ClN2O/c1-20-8-2-3-16(20)12-21-17-9-14(10-19-11-17)13-4-6-15(18)7-5-13/h4-7,9-11,16H,2-3,8,12H2,1H3/t16-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.0820	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro ability to displace [3H]-(-)-cytisine binding to whole rat brain membranes at Nicotinic acetylcholine receptor alpha4-beta2				Bioorg Med Chem Lett 11: 631-3 (2001) BindingDB Entry DOI: 10.7270/Q2WM1CPS
					More data for this Ligand-Target Pair