BDBM50097625 4-(3-Carbamimidoyl-phenyl)-2-methyl-thiazole-5-carboxylic acid (2'-sulfamoyl-biphenyl-4-yl)-amide; TFA::CHEMBL156924
SMILES: Cc1nc(c(s1)C(=O)Nc1ccc(cc1)-c1ccccc1S(N)(=O)=O)-c1cccc(c1)C(N)=N
InChI Key: InChIKey=CEPPRMSISLCFFG-UHFFFAOYSA-N
Data: 4 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Coagulation factor X (Homo sapiens (Human)) | BDBM50097625 (4-(3-Carbamimidoyl-phenyl)-2-methyl-thiazole-5-car...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.0600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
DuPont Pharmaceuticals Company Curated by ChEMBL | Assay Description Binding affinity towards Rabbit Coagulation factor X in a rabbit arterio-venous (A-V) shunt model | Bioorg Med Chem Lett 11: 641-5 (2001) BindingDB Entry DOI: 10.7270/Q2RV0MZ2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Oryctolagus cuniculus) | BDBM50097625 (4-(3-Carbamimidoyl-phenyl)-2-methyl-thiazole-5-car...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.0800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
DuPont Pharmaceuticals Company Curated by ChEMBL | Assay Description Binding affinity towards human trypsin | Bioorg Med Chem Lett 11: 641-5 (2001) BindingDB Entry DOI: 10.7270/Q2RV0MZ2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1/Trypsin-2/Trypsin-3 (Homo sapiens (Human)) | BDBM50097625 (4-(3-Carbamimidoyl-phenyl)-2-methyl-thiazole-5-car...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
DuPont Pharmaceuticals Company Curated by ChEMBL | Assay Description Binding affinity towards human trypsin | Bioorg Med Chem Lett 11: 641-5 (2001) BindingDB Entry DOI: 10.7270/Q2RV0MZ2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50097625 (4-(3-Carbamimidoyl-phenyl)-2-methyl-thiazole-5-car...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
DuPont Pharmaceuticals Company Curated by ChEMBL | Assay Description Binding affinity towards human thrombin | Bioorg Med Chem Lett 11: 641-5 (2001) BindingDB Entry DOI: 10.7270/Q2RV0MZ2 | |||||||||||
More data for this Ligand-Target Pair |