BDBM50097629 5-(3-Carbamimidoyl-phenyl)-2-methyl-1H-imidazole-4-carboxylic acid (2'-sulfamoyl-biphenyl-4-yl)-amide; TFA::CHEMBL159204

SMILES: Cc1nc(c([nH]1)C(=O)Nc1ccc(cc1)-c1ccccc1S(N)(=O)=O)-c1cccc(c1)C(N)=N

InChI Key: InChIKey=VLCAFAQOJLDAAP-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50097629   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50097629 (5-(3-Carbamimidoyl-phenyl)-2-methyl-1H-imidazole-4...) Show SMILES Cc1nc(c([nH]1)C(=O)Nc1ccc(cc1)-c1ccccc1S(N)(=O)=O)-c1cccc(c1)C(N)=N Show InChI InChI=1S/C24H22N6O3S/c1-14-28-21(16-5-4-6-17(13-16)23(25)26)22(29-14)24(31)30-18-11-9-15(10-12-18)19-7-2-3-8-20(19)34(27,32)33/h2-13H,1H3,(H3,25,26)(H,28,29)(H,30,31)(H2,27,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity towards human Serine protease FXa				Bioorg Med Chem Lett 11: 641-5 (2001) BindingDB Entry DOI: 10.7270/Q2RV0MZ2
					More data for this Ligand-Target Pair
Trypsin (Homo sapiens (Human))	BDBM50097629 (5-(3-Carbamimidoyl-phenyl)-2-methyl-1H-imidazole-4...) Show SMILES Cc1nc(c([nH]1)C(=O)Nc1ccc(cc1)-c1ccccc1S(N)(=O)=O)-c1cccc(c1)C(N)=N Show InChI InChI=1S/C24H22N6O3S/c1-14-28-21(16-5-4-6-17(13-16)23(25)26)22(29-14)24(31)30-18-11-9-15(10-12-18)19-7-2-3-8-20(19)34(27,32)33/h2-13H,1H3,(H3,25,26)(H,28,29)(H,30,31)(H2,27,32,33)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity towards human trypsin				Bioorg Med Chem Lett 11: 641-5 (2001) BindingDB Entry DOI: 10.7270/Q2RV0MZ2
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50097629 (5-(3-Carbamimidoyl-phenyl)-2-methyl-1H-imidazole-4...) Show SMILES Cc1nc(c([nH]1)C(=O)Nc1ccc(cc1)-c1ccccc1S(N)(=O)=O)-c1cccc(c1)C(N)=N Show InChI InChI=1S/C24H22N6O3S/c1-14-28-21(16-5-4-6-17(13-16)23(25)26)22(29-14)24(31)30-18-11-9-15(10-12-18)19-7-2-3-8-20(19)34(27,32)33/h2-13H,1H3,(H3,25,26)(H,28,29)(H,30,31)(H2,27,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity towards human thrombin				Bioorg Med Chem Lett 11: 641-5 (2001) BindingDB Entry DOI: 10.7270/Q2RV0MZ2
					More data for this Ligand-Target Pair