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SMILES: Cc1ccc(cc1)S(=O)(=O)NCc1ccc(cc1)C(=O)NCC1CCCN(Cc2ccccc2)C1

InChI Key: InChIKey=WZNQACDHUYJWDB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50097706   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kappa-type opioid receptor


(Homo sapiens (Human))		BDBM50097706
PNG
(CHEMBL3590202)
Show SMILES Cc1ccc(cc1)S(=O)(=O)NCc1ccc(cc1)C(=O)NCC1CCCN(Cc2ccccc2)C1
Show InChI InChI=1S/C35H46FN7O5S/c1-4-5-6-7-8-9-14-39(3)31(45)23-43-22-29(33(47)38-35(43)49-25-27-10-12-30(36)13-11-27)19-28-20-37-34(48)42(21-28)24-32(46)41-17-15-40(16-18-41)26(2)44/h10-13,20-22H,4-9,14-19,23-25H2,1-3H3
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Similars
Article
PubMed
n/an/a>1.80E+4n/an/an/an/an/an/a



University of Kansas Specialized Chemistry Center

Curated by ChEMBL


Assay Description
Antagonist activity against HA-tagged human recombinant kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by [35S]GTPgammaS bi...

Bioorg Med Chem 23: 3948-56 (2015)


Article DOI: 10.1016/j.bmc.2014.12.033
BindingDB Entry DOI: 10.7270/Q2R49SJX
More data for this
Ligand-Target Pair