BDBM50097792 (E)-3-(2-Naphthalen-2-ylmethyl-phenyl)-acrylic acid::3-(2-(naphthalen-2-ylmethyl)phenyl)acrylic acid::CHEMBL423815

SMILES: OC(=O)\C=C\c1ccccc1Cc1ccc2ccccc2c1

InChI Key: InChIKey=MOLQZQYMXCCLHS-VAWYXSNFSA-N

Data: 17 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50097792   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50097792 ((E)-3-(2-Naphthalen-2-ylmethyl-phenyl)-acrylic aci...) Show SMILES OC(=O)\C=C\c1ccccc1Cc1ccc2ccccc2c1 Show InChI InChI=1S/C20H16O2/c21-20(22)12-11-17-6-2-4-8-19(17)14-15-9-10-16-5-1-3-7-18(16)13-15/h1-13H,14H2,(H,21,22)/b12-11+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Antagonistic activity at Prostanoid EP3 receptor in human was determined				Bioorg Med Chem Lett 11: 747-9 (2001) BindingDB Entry DOI: 10.7270/Q2GB239F
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50097792 ((E)-3-(2-Naphthalen-2-ylmethyl-phenyl)-acrylic aci...) Show SMILES OC(=O)\C=C\c1ccccc1Cc1ccc2ccccc2c1 Show InChI InChI=1S/C20H16O2/c21-20(22)12-11-17-6-2-4-8-19(17)14-15-9-10-16-5-1-3-7-18(16)13-15/h1-13H,14H2,(H,21,22)/b12-11+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Binding affinity to EP3 receptor				Bioorg Med Chem Lett 16: 5639-42 (2006) Article DOI: 10.1016/j.bmcl.2006.08.025 BindingDB Entry DOI: 10.7270/Q2NS0VQ6
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50097792 ((E)-3-(2-Naphthalen-2-ylmethyl-phenyl)-acrylic aci...) Show SMILES OC(=O)\C=C\c1ccccc1Cc1ccc2ccccc2c1 Show InChI InChI=1S/C20H16O2/c21-20(22)12-11-17-6-2-4-8-19(17)14-15-9-10-16-5-1-3-7-18(16)13-15/h1-13H,14H2,(H,21,22)/b12-11+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Binding affinity to EP3 receptor in presence of HSA				Bioorg Med Chem Lett 16: 5639-42 (2006) Article DOI: 10.1016/j.bmcl.2006.08.025 BindingDB Entry DOI: 10.7270/Q2NS0VQ6
					More data for this Ligand-Target Pair
Prostanoid IP receptor (Homo sapiens (Human))	BDBM50097792 ((E)-3-(2-Naphthalen-2-ylmethyl-phenyl)-acrylic aci...) Show SMILES OC(=O)\C=C\c1ccccc1Cc1ccc2ccccc2c1 Show InChI InChI=1S/C20H16O2/c21-20(22)12-11-17-6-2-4-8-19(17)14-15-9-10-16-5-1-3-7-18(16)13-15/h1-13H,14H2,(H,21,22)/b12-11+	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Binding affinity to IP receptor				Bioorg Med Chem Lett 16: 5639-42 (2006) Article DOI: 10.1016/j.bmcl.2006.08.025 BindingDB Entry DOI: 10.7270/Q2NS0VQ6
					More data for this Ligand-Target Pair
Prostanoid DP receptor (Homo sapiens (Human))	BDBM50097792 ((E)-3-(2-Naphthalen-2-ylmethyl-phenyl)-acrylic aci...) Show SMILES OC(=O)\C=C\c1ccccc1Cc1ccc2ccccc2c1 Show InChI InChI=1S/C20H16O2/c21-20(22)12-11-17-6-2-4-8-19(17)14-15-9-10-16-5-1-3-7-18(16)13-15/h1-13H,14H2,(H,21,22)/b12-11+	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Binding affinity to DP receptor				Bioorg Med Chem Lett 16: 5639-42 (2006) Article DOI: 10.1016/j.bmcl.2006.08.025 BindingDB Entry DOI: 10.7270/Q2NS0VQ6
					More data for this Ligand-Target Pair
Prostanoid TP receptor (Homo sapiens (Human))	BDBM50097792 ((E)-3-(2-Naphthalen-2-ylmethyl-phenyl)-acrylic aci...) Show SMILES OC(=O)\C=C\c1ccccc1Cc1ccc2ccccc2c1 Show InChI InChI=1S/C20H16O2/c21-20(22)12-11-17-6-2-4-8-19(17)14-15-9-10-16-5-1-3-7-18(16)13-15/h1-13H,14H2,(H,21,22)/b12-11+	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Binding affinity to TP receptor				Bioorg Med Chem Lett 16: 5639-42 (2006) Article DOI: 10.1016/j.bmcl.2006.08.025 BindingDB Entry DOI: 10.7270/Q2NS0VQ6
					More data for this Ligand-Target Pair
Prostaglandin F2-alpha receptor (Homo sapiens (Human))	BDBM50097792 ((E)-3-(2-Naphthalen-2-ylmethyl-phenyl)-acrylic aci...) Show SMILES OC(=O)\C=C\c1ccccc1Cc1ccc2ccccc2c1 Show InChI InChI=1S/C20H16O2/c21-20(22)12-11-17-6-2-4-8-19(17)14-15-9-10-16-5-1-3-7-18(16)13-15/h1-13H,14H2,(H,21,22)/b12-11+	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Binding affinity to FP receptor				Bioorg Med Chem Lett 16: 5639-42 (2006) Article DOI: 10.1016/j.bmcl.2006.08.025 BindingDB Entry DOI: 10.7270/Q2NS0VQ6
					More data for this Ligand-Target Pair
Prostanoid DP receptor (Homo sapiens (Human))	BDBM50097792 ((E)-3-(2-Naphthalen-2-ylmethyl-phenyl)-acrylic aci...) Show SMILES OC(=O)\C=C\c1ccccc1Cc1ccc2ccccc2c1 Show InChI InChI=1S/C20H16O2/c21-20(22)12-11-17-6-2-4-8-19(17)14-15-9-10-16-5-1-3-7-18(16)13-15/h1-13H,14H2,(H,21,22)/b12-11+	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	530	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Antagonistic activity at Prostanoid DP receptor in human was determined				Bioorg Med Chem Lett 11: 747-9 (2001) BindingDB Entry DOI: 10.7270/Q2GB239F
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50097792 ((E)-3-(2-Naphthalen-2-ylmethyl-phenyl)-acrylic aci...) Show SMILES OC(=O)\C=C\c1ccccc1Cc1ccc2ccccc2c1 Show InChI InChI=1S/C20H16O2/c21-20(22)12-11-17-6-2-4-8-19(17)14-15-9-10-16-5-1-3-7-18(16)13-15/h1-13H,14H2,(H,21,22)/b12-11+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Antagonistic activity at Prostanoid EP4 receptor in human was determined				Bioorg Med Chem Lett 11: 747-9 (2001) BindingDB Entry DOI: 10.7270/Q2GB239F
					More data for this Ligand-Target Pair
Prostanoid TP receptor (Homo sapiens (Human))	BDBM50097792 ((E)-3-(2-Naphthalen-2-ylmethyl-phenyl)-acrylic aci...) Show SMILES OC(=O)\C=C\c1ccccc1Cc1ccc2ccccc2c1 Show InChI InChI=1S/C20H16O2/c21-20(22)12-11-17-6-2-4-8-19(17)14-15-9-10-16-5-1-3-7-18(16)13-15/h1-13H,14H2,(H,21,22)/b12-11+	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Antagonistic activity at Thromboxane A2 receptor in human was determined				Bioorg Med Chem Lett 11: 747-9 (2001) BindingDB Entry DOI: 10.7270/Q2GB239F
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50097792 ((E)-3-(2-Naphthalen-2-ylmethyl-phenyl)-acrylic aci...) Show SMILES OC(=O)\C=C\c1ccccc1Cc1ccc2ccccc2c1 Show InChI InChI=1S/C20H16O2/c21-20(22)12-11-17-6-2-4-8-19(17)14-15-9-10-16-5-1-3-7-18(16)13-15/h1-13H,14H2,(H,21,22)/b12-11+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Antagonistic activity at Prostanoid EP2 receptor in human was determined				Bioorg Med Chem Lett 11: 747-9 (2001) BindingDB Entry DOI: 10.7270/Q2GB239F
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50097792 ((E)-3-(2-Naphthalen-2-ylmethyl-phenyl)-acrylic aci...) Show SMILES OC(=O)\C=C\c1ccccc1Cc1ccc2ccccc2c1 Show InChI InChI=1S/C20H16O2/c21-20(22)12-11-17-6-2-4-8-19(17)14-15-9-10-16-5-1-3-7-18(16)13-15/h1-13H,14H2,(H,21,22)/b12-11+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Binding affinity to EP2 receptor				Bioorg Med Chem Lett 16: 5639-42 (2006) Article DOI: 10.1016/j.bmcl.2006.08.025 BindingDB Entry DOI: 10.7270/Q2NS0VQ6
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50097792 ((E)-3-(2-Naphthalen-2-ylmethyl-phenyl)-acrylic aci...) Show SMILES OC(=O)\C=C\c1ccccc1Cc1ccc2ccccc2c1 Show InChI InChI=1S/C20H16O2/c21-20(22)12-11-17-6-2-4-8-19(17)14-15-9-10-16-5-1-3-7-18(16)13-15/h1-13H,14H2,(H,21,22)/b12-11+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Binding affinity to EP4 receptor				Bioorg Med Chem Lett 16: 5639-42 (2006) Article DOI: 10.1016/j.bmcl.2006.08.025 BindingDB Entry DOI: 10.7270/Q2NS0VQ6
					More data for this Ligand-Target Pair
Prostaglandin F2-alpha receptor (Homo sapiens (Human))	BDBM50097792 ((E)-3-(2-Naphthalen-2-ylmethyl-phenyl)-acrylic aci...) Show SMILES OC(=O)\C=C\c1ccccc1Cc1ccc2ccccc2c1 Show InChI InChI=1S/C20H16O2/c21-20(22)12-11-17-6-2-4-8-19(17)14-15-9-10-16-5-1-3-7-18(16)13-15/h1-13H,14H2,(H,21,22)/b12-11+	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	6.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Antagonistic activity at Prostanoid FP receptor in human was determined				Bioorg Med Chem Lett 11: 747-9 (2001) BindingDB Entry DOI: 10.7270/Q2GB239F
					More data for this Ligand-Target Pair
Prostanoid IP receptor (Homo sapiens (Human))	BDBM50097792 ((E)-3-(2-Naphthalen-2-ylmethyl-phenyl)-acrylic aci...) Show SMILES OC(=O)\C=C\c1ccccc1Cc1ccc2ccccc2c1 Show InChI InChI=1S/C20H16O2/c21-20(22)12-11-17-6-2-4-8-19(17)14-15-9-10-16-5-1-3-7-18(16)13-15/h1-13H,14H2,(H,21,22)/b12-11+	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Antagonistic activity at Prostanoid IP receptor in human was determined				Bioorg Med Chem Lett 11: 747-9 (2001) BindingDB Entry DOI: 10.7270/Q2GB239F
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1) (Homo sapiens (Human))	BDBM50097792 ((E)-3-(2-Naphthalen-2-ylmethyl-phenyl)-acrylic aci...) Show SMILES OC(=O)\C=C\c1ccccc1Cc1ccc2ccccc2c1 Show InChI InChI=1S/C20H16O2/c21-20(22)12-11-17-6-2-4-8-19(17)14-15-9-10-16-5-1-3-7-18(16)13-15/h1-13H,14H2,(H,21,22)/b12-11+	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Binding affinity to EP1 receptor				Bioorg Med Chem Lett 16: 5639-42 (2006) Article DOI: 10.1016/j.bmcl.2006.08.025 BindingDB Entry DOI: 10.7270/Q2NS0VQ6
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (EP1) (Homo sapiens (Human))	BDBM50097792 ((E)-3-(2-Naphthalen-2-ylmethyl-phenyl)-acrylic aci...) Show SMILES OC(=O)\C=C\c1ccccc1Cc1ccc2ccccc2c1 Show InChI InChI=1S/C20H16O2/c21-20(22)12-11-17-6-2-4-8-19(17)14-15-9-10-16-5-1-3-7-18(16)13-15/h1-13H,14H2,(H,21,22)/b12-11+	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada & Co. Curated by ChEMBL					Assay Description Antagonistic activity at Prostanoid EP1 receptor in human was determined				Bioorg Med Chem Lett 11: 747-9 (2001) BindingDB Entry DOI: 10.7270/Q2GB239F
					More data for this Ligand-Target Pair