Found 4 hits for monomerid = 50097878 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50097878
(CHEMBL3589658)Show SMILES OC(=O)c1ccc2[nH]c3c(c(nc4ccccc34)C(O)=O)c2c1 Show InChI InChI=1S/C17H10N2O4/c20-16(21)8-5-6-12-10(7-8)13-14(18-12)9-3-1-2-4-11(9)19-15(13)17(22)23/h1-7,18H,(H,20,21)(H,22,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK2 using [gamma-33P]ATP as substrate after 30 mins by scintillation counting analysis |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50097878
(CHEMBL3589658)Show SMILES OC(=O)c1ccc2[nH]c3c(c(nc4ccccc34)C(O)=O)c2c1 Show InChI InChI=1S/C17H10N2O4/c20-16(21)8-5-6-12-10(7-8)13-14(18-12)9-3-1-2-4-11(9)19-15(13)17(22)23/h1-7,18H,(H,20,21)(H,22,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of ERK2 (unknown origin) |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50097878
(CHEMBL3589658)Show SMILES OC(=O)c1ccc2[nH]c3c(c(nc4ccccc34)C(O)=O)c2c1 Show InChI InChI=1S/C17H10N2O4/c20-16(21)8-5-6-12-10(7-8)13-14(18-12)9-3-1-2-4-11(9)19-15(13)17(22)23/h1-7,18H,(H,20,21)(H,22,23) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK1A expressed in Escherichia coli using RS peptide as substrate |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5
(Homo sapiens (Human)) | BDBM50097878
(CHEMBL3589658)Show SMILES OC(=O)c1ccc2[nH]c3c(c(nc4ccccc34)C(O)=O)c2c1 Show InChI InChI=1S/C17H10N2O4/c20-16(21)8-5-6-12-10(7-8)13-14(18-12)9-3-1-2-4-11(9)19-15(13)17(22)23/h1-7,18H,(H,20,21)(H,22,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK5 using [gamma-33P]ATP as substrate after 30 mins by scintillation counting analysis |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |