BDBM50097917 (3R,6R)-3-[Bis-(4-fluoro-phenyl)-methoxy]-6-methoxy-8-methyl-8-aza-bicyclo[3.2.1]octane::CHEMBL424565

SMILES: CO[C@@H]1CC2C[C@H](CC1N2C)OC(c1ccc(F)cc1)c1ccc(F)cc1

InChI Key: InChIKey=DRRFJWRBSWXNFW-GOLJUSPKSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50097917   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50097917 ((3R,6R)-3-[Bis-(4-fluoro-phenyl)-methoxy]-6-methox...) Show SMILES CO[C@@H]1CC2C[C@H](CC1N2C)OC(c1ccc(F)cc1)c1ccc(F)cc1 |TLB:11:6:9:3.2,THB:10:9:3.2:7.5.6,1:2:9:7.5.6| Show InChI InChI=1S/C22H25F2NO2/c1-25-18-11-19(13-20(25)21(12-18)26-2)27-22(14-3-7-16(23)8-4-14)15-5-9-17(24)10-6-15/h3-10,18-22H,11-13H2,1-2H3/t18?,19-,20?,21-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Ability to inhibit binding of [3H]paroxetine to Serotonin transporter in rat caudate putamen				Bioorg Med Chem Lett 11: 823-7 (2001) BindingDB Entry DOI: 10.7270/Q2PN965H
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50097917 ((3R,6R)-3-[Bis-(4-fluoro-phenyl)-methoxy]-6-methox...) Show SMILES CO[C@@H]1CC2C[C@H](CC1N2C)OC(c1ccc(F)cc1)c1ccc(F)cc1 |TLB:11:6:9:3.2,THB:10:9:3.2:7.5.6,1:2:9:7.5.6| Show InChI InChI=1S/C22H25F2NO2/c1-25-18-11-19(13-20(25)21(12-18)26-2)27-22(14-3-7-16(23)8-4-14)15-5-9-17(24)10-6-15/h3-10,18-22H,11-13H2,1-2H3/t18?,19-,20?,21-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Ferrara Curated by ChEMBL					Assay Description Ability to inhibit binding of [3H]WIN-35428 to dopamine transporter in rat caudate putamen				Bioorg Med Chem Lett 11: 823-7 (2001) BindingDB Entry DOI: 10.7270/Q2PN965H
					More data for this Ligand-Target Pair