BDBM50098108 CHEMBL283121::Sulfamic acid 4-bromo-phenyl ester

SMILES: NS(=O)(=O)Oc1ccc(Br)cc1

InChI Key: InChIKey=BLGCEUZOXJETEV-UHFFFAOYSA-N

Data: 4 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50098108   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50098108 (CHEMBL283121 | Sulfamic acid 4-bromo-phenyl ester) Show SMILES NS(=O)(=O)Oc1ccc(Br)cc1 Show InChI InChI=1S/C6H6BrNO3S/c7-5-1-3-6(4-2-5)11-12(8,9)10/h1-4H,(H2,8,9,10)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Montpellier II Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase II				J Med Chem 46: 2197-204 (2003) Article DOI: 10.1021/jm021124k BindingDB Entry DOI: 10.7270/Q28P617T
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50098108 (CHEMBL283121 | Sulfamic acid 4-bromo-phenyl ester) Show SMILES NS(=O)(=O)Oc1ccc(Br)cc1 Show InChI InChI=1S/C6H6BrNO3S/c7-5-1-3-6(4-2-5)11-12(8,9)10/h1-4H,(H2,8,9,10)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Union Life Sciences Ltd. Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow method				J Med Chem 55: 3513-20 (2012) Article DOI: 10.1021/jm300203r BindingDB Entry DOI: 10.7270/Q2RX9D4X
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50098108 (CHEMBL283121 | Sulfamic acid 4-bromo-phenyl ester) Show SMILES NS(=O)(=O)Oc1ccc(Br)cc1 Show InChI InChI=1S/C6H6BrNO3S/c7-5-1-3-6(4-2-5)11-12(8,9)10/h1-4H,(H2,8,9,10)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	7.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Montpellier II Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase I				J Med Chem 46: 2197-204 (2003) Article DOI: 10.1021/jm021124k BindingDB Entry DOI: 10.7270/Q28P617T
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50098108 (CHEMBL283121 | Sulfamic acid 4-bromo-phenyl ester) Show SMILES NS(=O)(=O)Oc1ccc(Br)cc1 Show InChI InChI=1S/C6H6BrNO3S/c7-5-1-3-6(4-2-5)11-12(8,9)10/h1-4H,(H2,8,9,10)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Montpellier II Curated by ChEMBL					Assay Description Inhibitory concentration against catalytic domain of human cloned carbonic anhydrase IX.				J Med Chem 46: 2197-204 (2003) Article DOI: 10.1021/jm021124k BindingDB Entry DOI: 10.7270/Q28P617T
					More data for this Ligand-Target Pair
Steryl-sulfatase (Homo sapiens (Human))	BDBM50098108 (CHEMBL283121 | Sulfamic acid 4-bromo-phenyl ester) Show SMILES NS(=O)(=O)Oc1ccc(Br)cc1 Show InChI InChI=1S/C6H6BrNO3S/c7-5-1-3-6(4-2-5)11-12(8,9)10/h1-4H,(H2,8,9,10)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	912	n/a	n/a	n/a	n/a	n/a	n/a
Kingston University Curated by ChEMBL					Assay Description In vitro inhibition of estrone sulfatase.				Bioorg Med Chem Lett 12: 1279-82 (2002) BindingDB Entry DOI: 10.7270/Q2MC90K1
					More data for this Ligand-Target Pair
Steryl-sulfatase (Homo sapiens (Human))	BDBM50098108 (CHEMBL283121 | Sulfamic acid 4-bromo-phenyl ester) Show SMILES NS(=O)(=O)Oc1ccc(Br)cc1 Show InChI InChI=1S/C6H6BrNO3S/c7-5-1-3-6(4-2-5)11-12(8,9)10/h1-4H,(H2,8,9,10)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	9.12E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kingston University Curated by ChEMBL					Assay Description Inhibitory concentration against estrone sulfatase				Bioorg Med Chem Lett 11: 899-902 (2001) BindingDB Entry DOI: 10.7270/Q25M6678
					More data for this Ligand-Target Pair