null
SMILES: Cc1ccc2n(CCCCC3(C(=O)NCC(F)(F)F)c4ccccc4-c4ccccc34)cnc2c1NC(=O)c1ccccc1-c1ccc(cc1)C(F)(F)F
InChI Key: InChIKey=JSERVZZVBREDDK-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Microsomal triglyceride transfer protein large subunit (Homo sapiens (Human)) | BDBM50098322 (9-(4-{5-Methyl-4-[(4'-trifluoromethyl-biphenyl-2-c...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
The Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of human Microsomal Triglyceride Transfer Protein, (triglyceride transfer assay) | J Med Chem 44: 851-6 (2001) BindingDB Entry DOI: 10.7270/Q2N015S8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Microsomal triglyceride transfer protein large subunit (Homo sapiens (Human)) | BDBM50098322 (9-(4-{5-Methyl-4-[(4'-trifluoromethyl-biphenyl-2-c...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 0.0200 | n/a | n/a | n/a | n/a | n/a | n/a |
The Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro inhibition of human microsomal triglyceride transfer protein in HepG2 cells using apoB secretion assay | J Med Chem 44: 851-6 (2001) BindingDB Entry DOI: 10.7270/Q2N015S8 | |||||||||||
More data for this Ligand-Target Pair |