BDBM50098527 1-Methyl-2-(8-trifluoromethyl-2,3,6,7-tetrahydro-benzo[1,2-b;4,5-b']difuran-4-yl)-ethyl-ammonium; chloride::CHEMBL6452
SMILES: C[C@@H]([NH3+])Cc1c2CCOc2c(c2CCOc12)C(F)(F)F
InChI Key: InChIKey=KMWGSFWAZUVTCM-SSDOTTSWSA-O
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50098527 (1-Methyl-2-(8-trifluoromethyl-2,3,6,7-tetrahydro-b...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Binding affinity at cloned rat 5-hydroxytryptamine 2A receptor using [3H]-DOB as radioligand | J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat)) | BDBM50098527 (1-Methyl-2-(8-trifluoromethyl-2,3,6,7-tetrahydro-b...) | KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Binding affinity at cloned rat 5-hydroxytryptamine 2C receptor using [3H]-DOI as radioligand | J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50098527 (1-Methyl-2-(8-trifluoromethyl-2,3,6,7-tetrahydro-b...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 28 | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Ability to stimulate phosphoinositide hydrolysis in NIH3T3 cells expressing the 5-hydroxytryptamine 2A receptor | J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND | |||||||||||
More data for this Ligand-Target Pair |