BDBM50098532 2-(8-Bromo-2,3,6,7-tetrahydro-benzo[1,2-b;4,5-b']difuran-4-yl)-1-methyl-ethyl-ammonium; chloride::CHEMBL6710
SMILES: C[C@@H]([NH3+])Cc1c2CCOc2c(Br)c2CCOc12
InChI Key: InChIKey=FKRREVSELFOLDT-SSDOTTSWSA-O
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat)) | BDBM50098532 (2-(8-Bromo-2,3,6,7-tetrahydro-benzo[1,2-b;4,5-b']d...) | KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.260 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Binding affinity at cloned rat 5-hydroxytryptamine 2C receptor using [3H]-DOI as radioligand | J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50098532 (2-(8-Bromo-2,3,6,7-tetrahydro-benzo[1,2-b;4,5-b']d...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Binding affinity at cloned rat 5-hydroxytryptamine 2A receptor using [3H]-DOB as radioligand | J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50098532 (2-(8-Bromo-2,3,6,7-tetrahydro-benzo[1,2-b;4,5-b']d...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 8.38 | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Ability to stimulate phosphoinositide hydrolysis in NIH3T3 cells expressing the 5-hydroxytryptamine 2A receptor | J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND | |||||||||||
More data for this Ligand-Target Pair |