BDBM50098655 CHEMBL3594308

SMILES: Nc1nccc2cc(NC(C(=O)NCc3ccccc3)c3ccccc3)ccc12

InChI Key: InChIKey=JJJKCNGQRVGVDX-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50098655   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor III/Factor VIIa (fVIIa) (Homo sapiens (Human))	BDBM50098655 (CHEMBL3594308) Show SMILES Nc1nccc2cc(NC(C(=O)NCc3ccccc3)c3ccccc3)ccc12 Show InChI InChI=1S/C24H22N4O/c25-23-21-12-11-20(15-19(21)13-14-26-23)28-22(18-9-5-2-6-10-18)24(29)27-16-17-7-3-1-4-8-17/h1-15,22,28H,16H2,(H2,25,26)(H,27,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human recombinant TF/F7a complex using S2288 as substrate preincubated for 15 mins followed by protein addition measured for 60 mins				J Med Chem 58: 6225-36 (2015) Article DOI: 10.1021/acs.jmedchem.5b00788 BindingDB Entry DOI: 10.7270/Q2DN46TN
					More data for this Ligand-Target Pair