BDBM50098787 CHEMBL3593468

SMILES: Clc1cc(Cl)cc(N\N=C(/C#N)C(=O)c2cc(on2)C2CCCCC2)c1

InChI Key: InChIKey=YKPVPCAWLCGOCD-XQNSMLJCSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50098787   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rap guanine nucleotide exchange factor 3 (Homo sapiens (Human))	BDBM50098787 (CHEMBL3593468) Show SMILES Clc1cc(Cl)cc(N\N=C(/C#N)C(=O)c2cc(on2)C2CCCCC2)c1 Show InChI InChI=1S/C18H16Cl2N4O2/c19-12-6-13(20)8-14(7-12)22-23-16(10-21)18(25)15-9-17(26-24-15)11-4-2-1-3-5-11/h6-9,11,22H,1-5H2/b23-16+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Antagonist activity at human recombinant EPAC1 assessed as inhibition of Rap1b-bGDP exchange activity				J Med Chem 58: 6033-47 (2015) Article DOI: 10.1021/acs.jmedchem.5b00635 BindingDB Entry DOI: 10.7270/Q29025JD
					More data for this Ligand-Target Pair
Rap guanine nucleotide exchange factor 4 (Mus musculus)	BDBM50098787 (CHEMBL3593468) Show SMILES Clc1cc(Cl)cc(N\N=C(/C#N)C(=O)c2cc(on2)C2CCCCC2)c1 Show InChI InChI=1S/C18H16Cl2N4O2/c19-12-6-13(20)8-14(7-12)22-23-16(10-21)18(25)15-9-17(26-24-15)11-4-2-1-3-5-11/h6-9,11,22H,1-5H2/b23-16+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assay				J Med Chem 58: 6033-47 (2015) Article DOI: 10.1021/acs.jmedchem.5b00635 BindingDB Entry DOI: 10.7270/Q29025JD
					More data for this Ligand-Target Pair