BDBM50098825 CHEMBL284433::N-[1-(5-tert-Butyl-[1,3,4]oxadiazole-2-carbonyl)-2-methyl-propyl]-2-(4-isobutyl-2,5-dioxo-imidazolidin-1-yl)-acetamide

SMILES: CC(C)Cc1[nH]c(=O)n(CC(=O)N[C@@H](C(C)C)C(=O)c2nnc(o2)C(C)(C)C)c1O

InChI Key: InChIKey=RZRDGKOBQPPIAS-AWEZNQCLSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50098825   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukocyte elastase (Homo sapiens (Human))	BDBM50098825 (CHEMBL284433 | N-[1-(5-tert-Butyl-[1,3,4]oxadiazol...) Show SMILES CC(C)Cc1[nH]c(=O)n(CC(=O)N[C@@H](C(C)C)C(=O)c2nnc(o2)C(C)(C)C)c1O Show InChI InChI=1S/C20H31N5O5/c1-10(2)8-12-17(28)25(19(29)21-12)9-13(26)22-14(11(3)4)15(27)16-23-24-18(30-16)20(5,6)7/h10-11,14,28H,8-9H2,1-7H3,(H,21,29)(H,22,26)/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	730	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cortech, Inc. Curated by ChEMBL					Assay Description Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrate				J Med Chem 44: 1268-85 (2001) BindingDB Entry DOI: 10.7270/Q2B858VW
					More data for this Ligand-Target Pair