BDBM50098834 1-(3H-Imidazole-4-carbonyl)-2,3-dihydro-1H-indole-2-carboxylic acid [1-(5-tert-butyl-[1,3,4]oxadiazole-2-carbonyl)-2-methyl-propyl]-amide; hydrochloride::CHEMBL544444

SMILES: CC(C)[C@H](NC(=O)[C@@H]1Cc2ccccc2N1C(=O)c1cnc[nH]1)C(=O)c1nnc(o1)C(C)(C)C

InChI Key: InChIKey=XMUOKKONPWRBMK-ROUUACIJSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50098834   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukocyte elastase (Homo sapiens (Human))	BDBM50098834 (1-(3H-Imidazole-4-carbonyl)-2,3-dihydro-1H-indole-...) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1Cc2ccccc2N1C(=O)c1cnc[nH]1)C(=O)c1nnc(o1)C(C)(C)C Show InChI InChI=1S/C24H28N6O4/c1-13(2)18(19(31)21-28-29-23(34-21)24(3,4)5)27-20(32)17-10-14-8-6-7-9-16(14)30(17)22(33)15-11-25-12-26-15/h6-9,11-13,17-18H,10H2,1-5H3,(H,25,26)(H,27,32)/t17-,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	79.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cortech, Inc. Curated by ChEMBL					Assay Description Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrate				J Med Chem 44: 1268-85 (2001) BindingDB Entry DOI: 10.7270/Q2B858VW
					More data for this Ligand-Target Pair