BDBM50098838 2-{2-[2-(5-Amino-6-oxo-2-m-tolyl-6H-pyrimidin-1-yl)-acetylamino]-3-phenyl-propionyl}-benzooxazole-5-carboxylic acid methyl ester::CHEMBL26286

SMILES: COC(=O)c1ccc2oc(nc2c1)C(=O)C(Cc1ccccc1)NC(=O)Cn1c(ncc(N)c1=O)-c1cccc(C)c1

InChI Key: InChIKey=YFZBJEZECVJTBZ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50098838   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Chymase (Homo sapiens (Human))	BDBM50098838 (2-{2-[2-(5-Amino-6-oxo-2-m-tolyl-6H-pyrimidin-1-yl...) Show SMILES COC(=O)c1ccc2oc(nc2c1)C(=O)C(Cc1ccccc1)NC(=O)Cn1c(ncc(N)c1=O)-c1cccc(C)c1 Show InChI InChI=1S/C31H27N5O6/c1-18-7-6-10-20(13-18)28-33-16-22(32)30(39)36(28)17-26(37)34-24(14-19-8-4-3-5-9-19)27(38)29-35-23-15-21(31(40)41-2)11-12-25(23)42-29/h3-13,15-16,24H,14,17,32H2,1-2H3,(H,34,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	44.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Welfide Corporation Curated by ChEMBL					Assay Description Inhibitory activity evaluated against chymase from human heart.				J Med Chem 44: 1286-96 (2001) BindingDB Entry DOI: 10.7270/Q26H4J4K
					More data for this Ligand-Target Pair
Alpha-chymotrypsin (Bos taurus (bovine))	BDBM50098838 (2-{2-[2-(5-Amino-6-oxo-2-m-tolyl-6H-pyrimidin-1-yl...) Show SMILES COC(=O)c1ccc2oc(nc2c1)C(=O)C(Cc1ccccc1)NC(=O)Cn1c(ncc(N)c1=O)-c1cccc(C)c1 Show InChI InChI=1S/C31H27N5O6/c1-18-7-6-10-20(13-18)28-33-16-22(32)30(39)36(28)17-26(37)34-24(14-19-8-4-3-5-9-19)27(38)29-35-23-15-21(31(40)41-2)11-12-25(23)42-29/h3-13,15-16,24H,14,17,32H2,1-2H3,(H,34,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	47.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Welfide Corporation Curated by ChEMBL					Assay Description Inhibitory activity against alpha chymotrypsin from bovine pancreas.				J Med Chem 44: 1286-96 (2001) BindingDB Entry DOI: 10.7270/Q26H4J4K
					More data for this Ligand-Target Pair