BDBM50099176 CHEMBL176313::N-[(R)-2-(1H-Indol-3-yl)-1-(4-phenyl-1H-imidazol-2-yl)-ethyl]-4-trifluoromethoxy-benzamidine
SMILES: NC(=N[C@H](Cc1c[nH]c2ccccc12)c1nc(c[nH]1)-c1ccccc1)c1ccc(OC(F)(F)F)cc1
InChI Key: InChIKey=GLRQVFXONJDZOI-HSZRJFAPSA-N
Data: 5 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Somatostatin receptor type 3 (Homo sapiens (Human)) | BDBM50099176 (CHEMBL176313 | N-[(R)-2-(1H-Indol-3-yl)-1-(4-pheny...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 410 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour Curated by ChEMBL | Assay Description Inhibition of human sst3 receptor expressed in CHO cells | Bioorg Med Chem Lett 11: 991-5 (2001) BindingDB Entry DOI: 10.7270/Q2D50NHN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 5 (Homo sapiens (Human)) | BDBM50099176 (CHEMBL176313 | N-[(R)-2-(1H-Indol-3-yl)-1-(4-pheny...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour Curated by ChEMBL | Assay Description Inhibition of human sst5 receptor expressed in CHO cells | Bioorg Med Chem Lett 11: 991-5 (2001) BindingDB Entry DOI: 10.7270/Q2D50NHN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 1 (Homo sapiens (Human)) | BDBM50099176 (CHEMBL176313 | N-[(R)-2-(1H-Indol-3-yl)-1-(4-pheny...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.57E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour Curated by ChEMBL | Assay Description Inhibition of human sst1 receptor expressed in CHO cells | Bioorg Med Chem Lett 11: 991-5 (2001) BindingDB Entry DOI: 10.7270/Q2D50NHN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 4 (Homo sapiens (Human)) | BDBM50099176 (CHEMBL176313 | N-[(R)-2-(1H-Indol-3-yl)-1-(4-pheny...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.97E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour Curated by ChEMBL | Assay Description Inhibition of human sst4 receptor expressed in CHO cells | Bioorg Med Chem Lett 11: 991-5 (2001) BindingDB Entry DOI: 10.7270/Q2D50NHN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 2 (Homo sapiens (Human)) | BDBM50099176 (CHEMBL176313 | N-[(R)-2-(1H-Indol-3-yl)-1-(4-pheny...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour Curated by ChEMBL | Assay Description Inhibition of human sst2 receptor expressed in CHO cells | Bioorg Med Chem Lett 11: 991-5 (2001) BindingDB Entry DOI: 10.7270/Q2D50NHN | |||||||||||
More data for this Ligand-Target Pair |