BDBM50099566 (2-fluorophenyl)-(4-fluorophenyl)phenylacetamide::2-(4-Fluoro-phenyl)-2-(2-fluoro-phenyl)-2-phenyl-acetamide::CHEMBL42205

SMILES: NC(=O)C(c1ccccc1)(c1ccc(F)cc1)c1ccccc1F

InChI Key: InChIKey=UFALWTGZIJAUPP-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50099566   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated potassium channel beta subunit Mink/subunit Kv7.1 (Homo sapiens (Human))	BDBM50099566 ((2-fluorophenyl)-(4-fluorophenyl)phenylacetamide |...) Show SMILES NC(=O)C(c1ccccc1)(c1ccc(F)cc1)c1ccccc1F Show InChI InChI=1S/C20H15F2NO/c21-16-12-10-15(11-13-16)20(19(23)24,14-6-2-1-3-7-14)17-8-4-5-9-18(17)22/h1-13H,(H2,23,24)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of Iks current KvLQT1 potassium channel				J Med Chem 44: 1627-53 (2001) BindingDB Entry DOI: 10.7270/Q218376D
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM50099566 ((2-fluorophenyl)-(4-fluorophenyl)phenylacetamide |...) Show SMILES NC(=O)C(c1ccccc1)(c1ccc(F)cc1)c1ccccc1F Show InChI InChI=1S/C20H15F2NO/c21-16-12-10-15(11-13-16)20(19(23)24,14-6-2-1-3-7-14)17-8-4-5-9-18(17)22/h1-13H,(H2,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Icagen, Inc. Curated by ChEMBL					Assay Description Inhibition of Gardos channel in human RBC assessed as inhibition of ionomycin-stimulated [86Rb] efflux				J Med Chem 51: 976-82 (2008) Article DOI: 10.1021/jm070663s BindingDB Entry DOI: 10.7270/Q23F4QGH
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4/Voltage-gated potassium channel beta subunit Mink/Voltage-gated potassium channel subunit Kv7.1 (Homo sapiens (Human))	BDBM50099566 ((2-fluorophenyl)-(4-fluorophenyl)phenylacetamide |...) Show SMILES NC(=O)C(c1ccccc1)(c1ccc(F)cc1)c1ccccc1F Show InChI InChI=1S/C20H15F2NO/c21-16-12-10-15(11-13-16)20(19(23)24,14-6-2-1-3-7-14)17-8-4-5-9-18(17)22/h1-13H,(H2,23,24)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Selectivity for gardos channel; (Gardos channel vs 2000 nM for the cardiac IKs channel).)				J Med Chem 44: 1627-53 (2001) BindingDB Entry DOI: 10.7270/Q218376D
					More data for this Ligand-Target Pair