BDBM50099669 CHEMBL295139::Succinic acid benzyl ester 3-carboxymethyl-1-(4-chloro-benzoyl)-2-methyl-1H-indol-5-yl ester

SMILES: Cc1c(CC(O)=O)c2cc(OC(=O)CCC(=O)OCc3ccccc3)ccc2n1C(=O)c1ccc(Cl)cc1

InChI Key: InChIKey=QVDAJXFPQSTEKZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50099669   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldose reductase (ALR2) (Bos taurus (Cattle))	BDBM50099669 (CHEMBL295139 | Succinic acid benzyl ester 3-carbox...) Show SMILES Cc1c(CC(O)=O)c2cc(OC(=O)CCC(=O)OCc3ccccc3)ccc2n1C(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C29H24ClNO7/c1-18-23(16-26(32)33)24-15-22(11-12-25(24)31(18)29(36)20-7-9-21(30)10-8-20)38-28(35)14-13-27(34)37-17-19-5-3-2-4-6-19/h2-12,15H,13-14,16-17H2,1H3,(H,32,33)	PDB GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of Aldose reductase (AR)				J Med Chem 44: 1718-28 (2001) BindingDB Entry DOI: 10.7270/Q2N0177X
					More data for this Ligand-Target Pair