BDBM50099778 4-Phenyl-[1,2]naphthoquinone::CHEMBL51447

SMILES: O=C1C=C(c2ccccc2)c2ccccc2C1=O

InChI Key: InChIKey=YDYHFBSKZVOOSR-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50099778   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukocyte common antigen (Homo sapiens (Human))	BDBM50099778 (4-Phenyl-[1,2]naphthoquinone | CHEMBL51447) Show SMILES O=C1C=C(c2ccccc2)c2ccccc2C1=O |t:2| Show InChI InChI=1S/C16H10O2/c17-15-10-14(11-6-2-1-3-7-11)12-8-4-5-9-13(12)16(15)18/h1-10H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against the cytosolic portion of CD45 protein-tyrosine phosphatase using pNPP as the substrate				J Med Chem 44: 1777-93 (2001) BindingDB Entry DOI: 10.7270/Q2X34WQQ
					More data for this Ligand-Target Pair
Dual specificity phosphatase Cdc25B (Homo sapiens (Human))	BDBM50099778 (4-Phenyl-[1,2]naphthoquinone | CHEMBL51447) Show SMILES O=C1C=C(c2ccccc2)c2ccccc2C1=O |t:2| Show InChI InChI=1S/C16H10O2/c17-15-10-14(11-6-2-1-3-7-11)12-8-4-5-9-13(12)16(15)18/h1-10H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	9.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description In vitro inhibitory activity of the compound against recombinant human Cdc25B using fluoreacein diphosphate (FDP) as a substrate				Bioorg Med Chem Lett 12: 1941-6 (2002) BindingDB Entry DOI: 10.7270/Q2QZ2999
					More data for this Ligand-Target Pair
Leukocyte common antigen (Homo sapiens (Human))	BDBM50099778 (4-Phenyl-[1,2]naphthoquinone | CHEMBL51447) Show SMILES O=C1C=C(c2ccccc2)c2ccccc2C1=O |t:2| Show InChI InChI=1S/C16H10O2/c17-15-10-14(11-6-2-1-3-7-11)12-8-4-5-9-13(12)16(15)18/h1-10H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	840	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description In vitro inhibitory activity of the compound against recombinant human CD45 using fluoreacein diphosphate (FDP) as a substrate				Bioorg Med Chem Lett 12: 1941-6 (2002) BindingDB Entry DOI: 10.7270/Q2QZ2999
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein phosphatase F (LAR) (Homo sapiens (Human))	BDBM50099778 (4-Phenyl-[1,2]naphthoquinone | CHEMBL51447) Show SMILES O=C1C=C(c2ccccc2)c2ccccc2C1=O |t:2| Show InChI InChI=1S/C16H10O2/c17-15-10-14(11-6-2-1-3-7-11)12-8-4-5-9-13(12)16(15)18/h1-10H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.49E+3	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description In vitro inhibitory activity of the compound against recombinant human LAR using fluoreacein diphosphate (FDP) as a substrate				Bioorg Med Chem Lett 12: 1941-6 (2002) BindingDB Entry DOI: 10.7270/Q2QZ2999
					More data for this Ligand-Target Pair
Protein-tyrosine phosphatase 1B (Homo sapiens (Human))	BDBM50099778 (4-Phenyl-[1,2]naphthoquinone | CHEMBL51447) Show SMILES O=C1C=C(c2ccccc2)c2ccccc2C1=O |t:2| Show InChI InChI=1S/C16H10O2/c17-15-10-14(11-6-2-1-3-7-11)12-8-4-5-9-13(12)16(15)18/h1-10H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluoreacein diphosphate (FDP) as a substrate				Bioorg Med Chem Lett 12: 1941-6 (2002) BindingDB Entry DOI: 10.7270/Q2QZ2999
					More data for this Ligand-Target Pair