BDBM50099809 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-benzyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL53102

SMILES: COc1c(cc(Br)c2ccccc12)C(=O)NC[C@H]1CCCN1Cc1ccccc1

InChI Key: InChIKey=UGGRLDVMPAOIFF-GOSISDBHSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50099809   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM50099809 (4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1...) Show SMILES COc1c(cc(Br)c2ccccc12)C(=O)NC[C@H]1CCCN1Cc1ccccc1 Show InChI InChI=1S/C24H25BrN2O2/c1-29-23-20-12-6-5-11-19(20)22(25)14-21(23)24(28)26-15-18-10-7-13-27(18)16-17-8-3-2-4-9-17/h2-6,8-9,11-12,14,18H,7,10,13,15-16H2,1H3,(H,26,28)/t18-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for dopamine receptor D3 expressed in Sf9 cells using [125I]-IABN the radioligand.				J Med Chem 44: 1815-26 (2001) BindingDB Entry DOI: 10.7270/Q2NK3DBZ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50099809 (4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1...) Show SMILES COc1c(cc(Br)c2ccccc12)C(=O)NC[C@H]1CCCN1Cc1ccccc1 Show InChI InChI=1S/C24H25BrN2O2/c1-29-23-20-12-6-5-11-19(20)22(25)14-21(23)24(28)26-15-18-10-7-13-27(18)16-17-8-3-2-4-9-17/h2-6,8-9,11-12,14,18H,7,10,13,15-16H2,1H3,(H,26,28)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	11.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for dopamine receptor D2 long expressed in Sf9 cells using [125I]-IABN radioligand.				J Med Chem 44: 1815-26 (2001) BindingDB Entry DOI: 10.7270/Q2NK3DBZ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50099809 (4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1...) Show SMILES COc1c(cc(Br)c2ccccc12)C(=O)NC[C@H]1CCCN1Cc1ccccc1 Show InChI InChI=1S/C24H25BrN2O2/c1-29-23-20-12-6-5-11-19(20)22(25)14-21(23)24(28)26-15-18-10-7-13-27(18)16-17-8-3-2-4-9-17/h2-6,8-9,11-12,14,18H,7,10,13,15-16H2,1H3,(H,26,28)/t18-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University School of Medicine Curated by ChEMBL					Assay Description Binding affinity for sigma-1 receptor measured on guinea pig brain membranes using [3H]-(+)-pentazocine as radioligand.				J Med Chem 44: 1815-26 (2001) BindingDB Entry DOI: 10.7270/Q2NK3DBZ
					More data for this Ligand-Target Pair