BDBM50099914 4-[4-(2,4-Dimethoxy-phenyl)-thiazol-2-yl]-5-methylsulfanyl-thiophene-2-carboxamidine::CHEMBL286267

SMILES: COc1ccc(-c2csc(n2)-c2cc(sc2SC)C(N)=N)c(OC)c1

InChI Key: InChIKey=OUPJOWDHCXNNFZ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50099914   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Complement C1s (Homo sapiens (Human))	BDBM50099914 (4-[4-(2,4-Dimethoxy-phenyl)-thiazol-2-yl]-5-methyl...) Show SMILES COc1ccc(-c2csc(n2)-c2cc(sc2SC)C(N)=N)c(OC)c1 Show InChI InChI=1S/C17H17N3O2S3/c1-21-9-4-5-10(13(6-9)22-2)12-8-24-16(20-12)11-7-14(15(18)19)25-17(11)23-3/h4-8H,1-3H3,(H3,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	640	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
3-Dimensional Pharmaceuticals Inc Curated by ChEMBL					Assay Description In vitro binding affinity towards human Complement C1s subcomponent				Bioorg Med Chem Lett 14: 3043-7 (2004) Article DOI: 10.1016/j.bmcl.2004.04.034 BindingDB Entry DOI: 10.7270/Q2K35T33
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50099914 (4-[4-(2,4-Dimethoxy-phenyl)-thiazol-2-yl]-5-methyl...) Show SMILES COc1ccc(-c2csc(n2)-c2cc(sc2SC)C(N)=N)c(OC)c1 Show InChI InChI=1S/C17H17N3O2S3/c1-21-9-4-5-10(13(6-9)22-2)12-8-24-16(20-12)11-7-14(15(18)19)25-17(11)23-3/h4-8H,1-3H3,(H3,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.52E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
3-Dimensional Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory activity against serine protease urokinase-type plasminogen activator (microPa)				Bioorg Med Chem Lett 11: 1379-82 (2001) BindingDB Entry DOI: 10.7270/Q24M93S1
					More data for this Ligand-Target Pair