BDBM50099935 4-(4-Benzo[b]thiophen-3-yl-thiazol-2-yl)-5-methylsulfanyl-thiophene-2-carboxamidine::CHEMBL28875

SMILES: CSc1sc(cc1-c1nc(cs1)-c1csc2ccccc12)C(N)=N

InChI Key: InChIKey=QHGDTGBHXYZJHD-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50099935   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Complement C1s (Homo sapiens (Human))	BDBM50099935 (4-(4-Benzo[b]thiophen-3-yl-thiazol-2-yl)-5-methyls...) Show SMILES CSc1sc(cc1-c1nc(cs1)-c1csc2ccccc12)C(N)=N Show InChI InChI=1S/C17H13N3S4/c1-21-17-10(6-14(24-17)15(18)19)16-20-12(8-23-16)11-7-22-13-5-3-2-4-9(11)13/h2-8H,1H3,(H3,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
3-Dimensional Pharmaceuticals Inc Curated by ChEMBL					Assay Description In vitro binding affinity towards human Complement C1s subcomponent				Bioorg Med Chem Lett 14: 3043-7 (2004) Article DOI: 10.1016/j.bmcl.2004.04.034 BindingDB Entry DOI: 10.7270/Q2K35T33
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50099935 (4-(4-Benzo[b]thiophen-3-yl-thiazol-2-yl)-5-methyls...) Show SMILES CSc1sc(cc1-c1nc(cs1)-c1csc2ccccc12)C(N)=N Show InChI InChI=1S/C17H13N3S4/c1-21-17-10(6-14(24-17)15(18)19)16-20-12(8-23-16)11-7-22-13-5-3-2-4-9(11)13/h2-8H,1H3,(H3,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.41E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
3-Dimensional Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory activity against serine protease urokinase-type plasminogen activator (microPa)				Bioorg Med Chem Lett 11: 1379-82 (2001) BindingDB Entry DOI: 10.7270/Q24M93S1
					More data for this Ligand-Target Pair