BDBM50099937 5-Methylsulfanyl-4-(4-phenoxymethyl-thiazol-2-yl)-thiophene-2-carboxamidine::CHEMBL287292

SMILES: CSc1sc(cc1-c1nc(COc2ccccc2)cs1)C(N)=N

InChI Key: InChIKey=WFUWFCPVIJPOGN-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50099937   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Complement C1s (Homo sapiens (Human))	BDBM50099937 (5-Methylsulfanyl-4-(4-phenoxymethyl-thiazol-2-yl)-...) Show SMILES CSc1sc(cc1-c1nc(COc2ccccc2)cs1)C(N)=N Show InChI InChI=1S/C16H15N3OS3/c1-21-16-12(7-13(23-16)14(17)18)15-19-10(9-22-15)8-20-11-5-3-2-4-6-11/h2-7,9H,8H2,1H3,(H3,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
3-Dimensional Pharmaceuticals Inc Curated by ChEMBL					Assay Description In vitro binding affinity towards human Complement C1s subcomponent				Bioorg Med Chem Lett 14: 3043-7 (2004) Article DOI: 10.1016/j.bmcl.2004.04.034 BindingDB Entry DOI: 10.7270/Q2K35T33
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50099937 (5-Methylsulfanyl-4-(4-phenoxymethyl-thiazol-2-yl)-...) Show SMILES CSc1sc(cc1-c1nc(COc2ccccc2)cs1)C(N)=N Show InChI InChI=1S/C16H15N3OS3/c1-21-16-12(7-13(23-16)14(17)18)15-19-10(9-22-15)8-20-11-5-3-2-4-6-11/h2-7,9H,8H2,1H3,(H3,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.78E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
3-Dimensional Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory activity against serine protease urokinase-type plasminogen activator (microPa)				Bioorg Med Chem Lett 11: 1379-82 (2001) BindingDB Entry DOI: 10.7270/Q24M93S1
					More data for this Ligand-Target Pair