BDBM50099962 (3-Benzyl-3H-benzoimidazol-5-yl)-quinazolin-4-yl-amine::CHEMBL281881

SMILES: C(c1ccccc1)n1cnc2ccc(Nc3ncnc4ccccc34)cc12

InChI Key: InChIKey=QGFNHEXCTWPTLL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50099962   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor protein-tyrosine kinase erbB-2 (Rattus norvegicus)	BDBM50099962 ((3-Benzyl-3H-benzoimidazol-5-yl)-quinazolin-4-yl-a...) Show SMILES C(c1ccccc1)n1cnc2ccc(Nc3ncnc4ccccc34)cc12 Show InChI InChI=1S/C22H17N5/c1-2-6-16(7-3-1)13-27-15-25-20-11-10-17(12-21(20)27)26-22-18-8-4-5-9-19(18)23-14-24-22/h1-12,14-15H,13H2,(H,23,24,26)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Research Biomet. Glaxo Wellcome Medicines Research Centre Curated by ChEMBL					Assay Description Inhibition of rat Receptor protein-tyrosine kinase erbB2				Bioorg Med Chem Lett 11: 1401-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VKB
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50099962 ((3-Benzyl-3H-benzoimidazol-5-yl)-quinazolin-4-yl-a...) Show SMILES C(c1ccccc1)n1cnc2ccc(Nc3ncnc4ccccc34)cc12 Show InChI InChI=1S/C22H17N5/c1-2-6-16(7-3-1)13-27-15-25-20-11-10-17(12-21(20)27)26-22-18-8-4-5-9-19(18)23-14-24-22/h1-12,14-15H,13H2,(H,23,24,26)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Research Biomet. Glaxo Wellcome Medicines Research Centre Curated by ChEMBL					Assay Description Inhibition of c-erbB-2 overexpressing HB4a cell proliferation				Bioorg Med Chem Lett 11: 1401-5 (2001) BindingDB Entry DOI: 10.7270/Q2W37VKB
					More data for this Ligand-Target Pair