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BDBM50100126 3-Isopropyl-4-methyl-pent-2-enoic acid 1-hydroxymethyl-2-(3-isopropyl-4-methyl-pentanoyloxy)-ethyl ester::CHEMBL38644
SMILES: [#6]-[#6](-[#6])-[#6](-[#6]-[#6](=O)-[#8]-[#6]-[#6@H](-[#6]-[#8])-[#8]-[#6](=O)\[#6]=[#6](\[#6](-[#6])-[#6])-[#6](-[#6])-[#6])-[#6](-[#6])-[#6]
InChI Key: InChIKey=OKIBGIFZZLLBIL-KRWDZBQOSA-N
Data: 2 KI
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Protein kinase C alpha type (Homo sapiens (Human)) | BDBM50100126 (3-Isopropyl-4-methyl-pent-2-enoic acid 1-hydroxyme...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Cancer Institute at Frederick Curated by ChEMBL | Assay Description Displacement of [20-3H]phorbol-12,13-dibutyrate (PDBu) from recombinant Protein kinase C alpha | J Med Chem 46: 1571-9 (2003) Article DOI: 10.1021/jm020476o BindingDB Entry DOI: 10.7270/Q2N58KQQ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein Kinase C, alpha (Bos taurus (bovine)) | BDBM50100126 (3-Isopropyl-4-methyl-pent-2-enoic acid 1-hydroxyme...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 31.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Cancer Institute at Frederick Curated by ChEMBL | Assay Description Ability to displace bound [20-3H]-PDBU from a recombinant single isozyme (PKCalpha) in the presence of phosphatidylserine | J Med Chem 44: 1892-904 (2001) BindingDB Entry DOI: 10.7270/Q2H995WH | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
