BDBM50100271 CHEMBL3326904
SMILES: CCCC(=O)c1cnn(c1C)-c1ccc(NC(=O)n2cc(CCCC(O)=O)c3ccc(C)cc23)cc1
InChI Key: InChIKey=CNEUIUYUJUBTAI-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Purinergic receptor P2Y12 (Rattus norvegicus) | BDBM50100271 (CHEMBL3326904) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sanofi R&D Curated by ChEMBL | Assay Description Antagonist activity at P2Y12 receptor in Sprague-Dawley rat platelet rich plasma assessed as inhibition of ADP-induced aggregation | J Med Chem 57: 7293-316 (2014) Article DOI: 10.1021/jm500588w BindingDB Entry DOI: 10.7270/Q2D79D21 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Purinergic receptor P2Y12 (Homo sapiens (Human)) | BDBM50100271 (CHEMBL3326904) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
Sanofi R&D Curated by ChEMBL | Assay Description Displacement of [33P]2MeS-ADP from P2Y12 receptor (unknown origin) transfected in CHO cells after 30 mins by scintillation counting analysis | J Med Chem 57: 7293-316 (2014) Article DOI: 10.1021/jm500588w BindingDB Entry DOI: 10.7270/Q2D79D21 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Purinergic receptor P2Y12 (Homo sapiens (Human)) | BDBM50100271 (CHEMBL3326904) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sanofi R&D Curated by ChEMBL | Assay Description Antagonist activity at P2Y12 receptor in human platelet rich plasma assessed as inhibition of ADP-induced aggregation | J Med Chem 57: 7293-316 (2014) Article DOI: 10.1021/jm500588w BindingDB Entry DOI: 10.7270/Q2D79D21 | |||||||||||
More data for this Ligand-Target Pair |