BDBM50100286 4-Imidazol-1-ylmethyl-2-(naphthalen-2-yloxy)-benzonitrile::CHEMBL22959

SMILES: N#Cc1ccc(Cn2ccnc2)cc1Oc1ccc2ccccc2c1

InChI Key: InChIKey=BECWPNYJZIVGFM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50100286   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50100286 (4-Imidazol-1-ylmethyl-2-(naphthalen-2-yloxy)-benzo...) Show SMILES N#Cc1ccc(Cn2ccnc2)cc1Oc1ccc2ccccc2c1 Show InChI InChI=1S/C21H15N3O/c22-13-19-6-5-16(14-24-10-9-23-15-24)11-21(19)25-20-8-7-17-3-1-2-4-18(17)12-20/h1-12,15H,14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of rate of incorporation of [3H]-FPP into recombinant Ras-CVIM by human farnesyltransferase.				Bioorg Med Chem Lett 11: 1257-60 (2001) BindingDB Entry DOI: 10.7270/Q2FX78RS
					More data for this Ligand-Target Pair
Geranylgeranyl transferase type I beta subunit/Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50100286 (4-Imidazol-1-ylmethyl-2-(naphthalen-2-yloxy)-benzo...) Show SMILES N#Cc1ccc(Cn2ccnc2)cc1Oc1ccc2ccccc2c1 Show InChI InChI=1S/C21H15N3O/c22-13-19-6-5-16(14-24-10-9-23-15-24)11-21(19)25-20-8-7-17-3-1-2-4-18(17)12-20/h1-12,15H,14H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of rate of incorporation of [3H]-GGPP into a biotinylated peptide corresponding to C-terminus of human Ki-Ras by human geranylgeranyl-tran...				Bioorg Med Chem Lett 11: 1257-60 (2001) BindingDB Entry DOI: 10.7270/Q2FX78RS
					More data for this Ligand-Target Pair