BDBM50100525 CHEMBL3327084
SMILES: FC(F)(F)c1ccc(NC(=O)NC2CCN(CC2)S(=O)(=O)C2CC2)cc1
InChI Key: InChIKey=FNQSAMVQHNDWBC-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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EBifunctional epoxide hydrolase 2 (Homo sapiens (Human)) | BDBM50100525 (CHEMBL3327084) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Davis Curated by ChEMBL | Assay Description Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assay | J Med Chem 57: 7016-30 (2014) Article DOI: 10.1021/jm500694p BindingDB Entry DOI: 10.7270/Q2FJ2JJQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Soluble epoxide hydrolase (sEH) (Mus musculus (Mouse)) | BDBM50100525 (CHEMBL3327084) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 9.30 | n/a | n/a | n/a | n/a | n/a | n/a |
The Regents of the University of California US Patent | Assay Description fluoresence competitive assay. | US Patent US9296693 (2016) BindingDB Entry DOI: 10.7270/Q2TX3D7M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Soluble epoxide hydrolase (sEH) (Mus musculus (Mouse)) | BDBM50100525 (CHEMBL3327084) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 92.1 | n/a | n/a | n/a | n/a | n/a | n/a |
The Regents of the University of California US Patent | Assay Description Trans-diphenylpropene oxide is used in a radiometric competitive assay. | US Patent US9296693 (2016) BindingDB Entry DOI: 10.7270/Q2TX3D7M | |||||||||||
More data for this Ligand-Target Pair |