BDBM50100974 CHEMBL317739
SMILES: C[C@@H](CNc1ncc(C)n(CC(=O)NCc2ccc3[nH]ncc3c2)c1=O)c1ccccc1
InChI Key: InChIKey=PXNBOFBSFXZTES-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prothrombin (Homo sapiens (Human)) | BDBM50100974 (CHEMBL317739) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 5.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Corvas International, Inc. Curated by ChEMBL | Assay Description In vitro inhibitory activity against human Thrombin (FIIa) cleavage of the chromogenic substrate | Bioorg Med Chem Lett 12: 2925-30 (2002) BindingDB Entry DOI: 10.7270/Q27946WJ | |||||||||||
More data for this Ligand-Target Pair |