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SMILES: CN(C)[C@]1(CC[C@H](N)CC1)c1ccccc1

InChI Key: InChIKey=KVRGHMFZWJMOBY-HDJSIYSDSA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50100994   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nociceptin receptor


(Homo sapiens (Human))		BDBM50100994
PNG
(CHEMBL3325882)
Show SMILES CN(C)[C@]1(CC[C@H](N)CC1)c1ccccc1 |r,wU:3.2,wD:6.6,(17.62,-17.1,;16.29,-16.33,;16.28,-14.79,;14.95,-17.11,;14.18,-18.44,;12.64,-18.44,;11.87,-17.11,;10.33,-17.11,;12.63,-15.78,;14.18,-15.78,;15.75,-18.43,;15,-19.77,;15.8,-21.09,;17.34,-21.06,;18.09,-19.7,;17.29,-18.39,)|
Show InChI InChI=1S/C14H22N2/c1-16(2)14(10-8-13(15)9-11-14)12-6-4-3-5-7-12/h3-7,13H,8-11,15H2,1-2H3/t13-,14-
PDB

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 120n/an/an/an/an/an/an/an/a



Pharmacokinetics

Curated by ChEMBL


Assay Description
Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells after 90 mins

ACS Med Chem Lett 5: 851-6 (2014)


Article DOI: 10.1021/ml500116x
BindingDB Entry DOI: 10.7270/Q28S4RPM
More data for this
Ligand-Target Pair