BDBM50101090 CHEMBL3326222
SMILES: Cl.Cl.CN(C)[C@]1(CC[C@@H](CC1)NCCc1c[nH]c2ccccc12)c1ccccc1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nociceptin receptor (Homo sapiens (Human)) | BDBM50101090 (CHEMBL3326222) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacokinetics Curated by ChEMBL | Assay Description Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells after 90 mins | ACS Med Chem Lett 5: 851-6 (2014) Article DOI: 10.1021/ml500116x BindingDB Entry DOI: 10.7270/Q28S4RPM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM50101090 (CHEMBL3326222) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 9.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacokinetics Curated by ChEMBL | Assay Description Displacement of [3H]Naloxone from human mu opioid receptor receptor expressed in CHO-K1 cells after 90 mins | ACS Med Chem Lett 5: 851-6 (2014) Article DOI: 10.1021/ml500116x BindingDB Entry DOI: 10.7270/Q28S4RPM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM50101090 (CHEMBL3326222) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 5.10E+4 | n/a | n/a | n/a | n/a |
Pharmacokinetics Curated by ChEMBL | Assay Description Agonist activity at human mu opioid receptor expressed in CHO-K1 cells assessed as stimulation of [35S]-GTPgammaS binding by scintillation proximity ... | ACS Med Chem Lett 5: 851-6 (2014) Article DOI: 10.1021/ml500116x BindingDB Entry DOI: 10.7270/Q28S4RPM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50101090 (CHEMBL3326222) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a |
Pharmacokinetics Curated by ChEMBL | Assay Description Agonist activity at human NOP receptor expressed in CHO-K1 cells assessed as stimulation of [35S]-GTPgammaS binding by scintillation proximity assay | ACS Med Chem Lett 5: 851-6 (2014) Article DOI: 10.1021/ml500116x BindingDB Entry DOI: 10.7270/Q28S4RPM | |||||||||||
More data for this Ligand-Target Pair |