BDBM50101410 (trans,trans)-1-bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene::5-[2-bromo-4-(3-carboxy-4-hydroxyphenethyl)phenethyl]-2-hydroxybenzoic acid::CHEMBL74704
SMILES: OC(=O)c1cc(\C=C\c2ccc(\C=C\c3ccc(O)c(c3)C(O)=O)c(Br)c2)ccc1O
InChI Key: InChIKey=ZVECSLHUCRIBDY-WMWQKROPSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta amyloid A4 protein (Homo sapiens (Human)) | BDBM50101410 ((trans,trans)-1-bromo-2,5-bis-(3-hydroxycarbonyl-4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Inhibitory activity against binding of [125I]-IMSB to amyloid beta in brain | J Med Chem 44: 2270-5 (2001) BindingDB Entry DOI: 10.7270/Q22J6B4Z | |||||||||||
More data for this Ligand-Target Pair |