BDBM50101504 CHEMBL77057::N*1*-{2-Cyclohexyl-1-[2-(4-dimethylamino-butylcarbamoyl)-ethylcarbamoyl]-ethyl}-N*4*-hydroxy-2-(3-p-tolyl-propyl)-succinamide

SMILES: CN(C)CCCCNC(=O)CCNC(=O)[C@H](CC1CCCCC1)NC(=O)[C@H](CCCc1ccc(C)cc1)CC(=O)NO

InChI Key: InChIKey=DKPQMSLWGNDZTO-IZLXSDGUSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50101504   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50101504 (CHEMBL77057 | N*1*-{2-Cyclohexyl-1-[2-(4-dimethyla...) Show SMILES CN(C)CCCCNC(=O)CCNC(=O)[C@H](CC1CCCCC1)NC(=O)[C@H](CCCc1ccc(C)cc1)CC(=O)NO Show InChI InChI=1S/C32H53N5O5/c1-24-14-16-25(17-15-24)12-9-13-27(23-30(39)36-42)31(40)35-28(22-26-10-5-4-6-11-26)32(41)34-20-18-29(38)33-19-7-8-21-37(2)3/h14-17,26-28,42H,4-13,18-23H2,1-3H3,(H,33,38)(H,34,41)(H,35,40)(H,36,39)/t27-,28+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.0200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Inhibitory constant against matrix metalloproteinase-2				J Med Chem 44: 2333-43 (2001) BindingDB Entry DOI: 10.7270/Q2JH3KFR
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50101504 (CHEMBL77057 | N*1*-{2-Cyclohexyl-1-[2-(4-dimethyla...) Show SMILES CN(C)CCCCNC(=O)CCNC(=O)[C@H](CC1CCCCC1)NC(=O)[C@H](CCCc1ccc(C)cc1)CC(=O)NO Show InChI InChI=1S/C32H53N5O5/c1-24-14-16-25(17-15-24)12-9-13-27(23-30(39)36-42)31(40)35-28(22-26-10-5-4-6-11-26)32(41)34-20-18-29(38)33-19-7-8-21-37(2)3/h14-17,26-28,42H,4-13,18-23H2,1-3H3,(H,33,38)(H,34,41)(H,35,40)(H,36,39)/t27-,28+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.87	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Inhibitory constant against matrix metalloproteinase-3				J Med Chem 44: 2333-43 (2001) BindingDB Entry DOI: 10.7270/Q2JH3KFR
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50101504 (CHEMBL77057 | N*1*-{2-Cyclohexyl-1-[2-(4-dimethyla...) Show SMILES CN(C)CCCCNC(=O)CCNC(=O)[C@H](CC1CCCCC1)NC(=O)[C@H](CCCc1ccc(C)cc1)CC(=O)NO Show InChI InChI=1S/C32H53N5O5/c1-24-14-16-25(17-15-24)12-9-13-27(23-30(39)36-42)31(40)35-28(22-26-10-5-4-6-11-26)32(41)34-20-18-29(38)33-19-7-8-21-37(2)3/h14-17,26-28,42H,4-13,18-23H2,1-3H3,(H,33,38)(H,34,41)(H,35,40)(H,36,39)/t27-,28+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	313	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Inhibitory constant against matrix metalloproteinase-1				J Med Chem 44: 2333-43 (2001) BindingDB Entry DOI: 10.7270/Q2JH3KFR
					More data for this Ligand-Target Pair