BDBM50101678 CHEMBL3394920

SMILES: CC(=O)Nc1ccc(cc1)C(=O)N\N=C\c1cc(Br)ccc1O

InChI Key: InChIKey=TVOOSQBQUHYYOC-GIJQJNRQSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50101678   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone chaperone ASF1A (Homo sapiens (Human))	BDBM50101678 (CHEMBL3394920) Show SMILES CC(=O)Nc1ccc(cc1)C(=O)N\N=C\c1cc(Br)ccc1O Show InChI InChI=1S/C16H14BrN3O3/c1-10(21)19-14-5-2-11(3-6-14)16(23)20-18-9-12-8-13(17)4-7-15(12)22/h2-9,22H,1H3,(H,19,21)(H,20,23)/b18-9+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Colorado State University Curated by ChEMBL					Assay Description Inhibition of His-tagged human Asf1a binding with H3/H4 assessed as fluorescence intensity after 30 mins by ALPHA assay				Bioorg Med Chem Lett 25: 963-8 (2015) Article DOI: 10.1016/j.bmcl.2014.11.067 BindingDB Entry DOI: 10.7270/Q2VM4F0G
					More data for this Ligand-Target Pair