BDBM50101680 CHEMBL3394918

SMILES: O=C(N\N=C\c1cccnc1)c1ccc(NC(=O)c2ccccc2)cc1

InChI Key: InChIKey=JURYGZJGNNQDQE-HYARGMPZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50101680   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone chaperone ASF1A (Homo sapiens (Human))	BDBM50101680 (CHEMBL3394918) Show SMILES O=C(N\N=C\c1cccnc1)c1ccc(NC(=O)c2ccccc2)cc1 Show InChI InChI=1S/C20H16N4O2/c25-19(16-6-2-1-3-7-16)23-18-10-8-17(9-11-18)20(26)24-22-14-15-5-4-12-21-13-15/h1-14H,(H,23,25)(H,24,26)/b22-14+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Colorado State University Curated by ChEMBL					Assay Description Inhibition of His-tagged human Asf1a binding with H3/H4 assessed as fluorescence intensity after 30 mins by ALPHA assay				Bioorg Med Chem Lett 25: 963-8 (2015) Article DOI: 10.1016/j.bmcl.2014.11.067 BindingDB Entry DOI: 10.7270/Q2VM4F0G
					More data for this Ligand-Target Pair