BDBM50101687 CHEMBL3394911

SMILES: COc1cc(\C=N\NC(=O)c2ccc(NC(=O)c3ccccc3)cc2)cc(Br)c1OCC(O)=O

InChI Key: InChIKey=FGACGCLZFKFALU-LGJNPRDNSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50101687   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone chaperone ASF1A (Homo sapiens (Human))	BDBM50101687 (CHEMBL3394911) Show SMILES COc1cc(\C=N\NC(=O)c2ccc(NC(=O)c3ccccc3)cc2)cc(Br)c1OCC(O)=O Show InChI InChI=1S/C24H20BrN3O6/c1-33-20-12-15(11-19(25)22(20)34-14-21(29)30)13-26-28-24(32)17-7-9-18(10-8-17)27-23(31)16-5-3-2-4-6-16/h2-13H,14H2,1H3,(H,27,31)(H,28,32)(H,29,30)/b26-13+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Colorado State University Curated by ChEMBL					Assay Description Inhibition of His-tagged human Asf1a binding with H3/H4 assessed as fluorescence intensity after 30 mins by ALPHA assay				Bioorg Med Chem Lett 25: 963-8 (2015) Article DOI: 10.1016/j.bmcl.2014.11.067 BindingDB Entry DOI: 10.7270/Q2VM4F0G
					More data for this Ligand-Target Pair