BDBM50101710 CHEMBL3394901

SMILES: COc1cc(\C=N\NC(=O)c2ccc(NC(=O)c3ccccc3OC)cc2)cc(Br)c1O

InChI Key: InChIKey=ZZUWYPBDCCCEGP-DHRITJCHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50101710   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone chaperone ASF1A (Homo sapiens (Human))	BDBM50101710 (CHEMBL3394901) Show SMILES COc1cc(\C=N\NC(=O)c2ccc(NC(=O)c3ccccc3OC)cc2)cc(Br)c1O Show InChI InChI=1S/C23H20BrN3O5/c1-31-19-6-4-3-5-17(19)23(30)26-16-9-7-15(8-10-16)22(29)27-25-13-14-11-18(24)21(28)20(12-14)32-2/h3-13,28H,1-2H3,(H,26,30)(H,27,29)/b25-13+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Colorado State University Curated by ChEMBL					Assay Description Inhibition of His-tagged human Asf1a binding with H3/H4 assessed as fluorescence intensity after 30 mins by ALPHA assay				Bioorg Med Chem Lett 25: 963-8 (2015) Article DOI: 10.1016/j.bmcl.2014.11.067 BindingDB Entry DOI: 10.7270/Q2VM4F0G
					More data for this Ligand-Target Pair