BDBM50101744 CHEMBL3394893

SMILES: COc1cc(\C=N\NC(=O)c2ccc(NC(C)=O)nc2)cc(Br)c1O

InChI Key: InChIKey=TZJRTGHDAYCHGF-FBCYGCLPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50101744   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone chaperone ASF1A (Homo sapiens (Human))	BDBM50101744 (CHEMBL3394893) Show SMILES COc1cc(\C=N\NC(=O)c2ccc(NC(C)=O)nc2)cc(Br)c1O Show InChI InChI=1S/C16H15BrN4O4/c1-9(22)20-14-4-3-11(8-18-14)16(24)21-19-7-10-5-12(17)15(23)13(6-10)25-2/h3-8,23H,1-2H3,(H,21,24)(H,18,20,22)/b19-7+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Colorado State University Curated by ChEMBL					Assay Description Inhibition of His-tagged human Asf1a binding with H3/H4 assessed as fluorescence intensity after 30 mins by ALPHA assay				Bioorg Med Chem Lett 25: 963-8 (2015) Article DOI: 10.1016/j.bmcl.2014.11.067 BindingDB Entry DOI: 10.7270/Q2VM4F0G
					More data for this Ligand-Target Pair