BDBM50101803 CHEMBL3398174
SMILES: COc1ccccc1-c1ccc2cnc(Nc3ccc(cc3OC)[C@@H]3CCN(CCO)C[C@@H]3O)nn12
InChI Key: InChIKey=UVPQQVIBGBMPDZ-RDPSFJRHSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM50101803 (CHEMBL3398174) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Teva Branded Pharmaceutical Products R&D, Inc. Curated by ChEMBL | Assay Description Inhibition of ALK (unknown origin) by enzymatic assay | Bioorg Med Chem Lett 25: 1047-52 (2015) Article DOI: 10.1016/j.bmcl.2015.01.019 BindingDB Entry DOI: 10.7270/Q2GB25SJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM50101803 (CHEMBL3398174) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Teva Branded Pharmaceutical Products R&D, Inc. Curated by ChEMBL | Assay Description Inhibition of ALK (unknown origin) by cellular assay | Bioorg Med Chem Lett 25: 1047-52 (2015) Article DOI: 10.1016/j.bmcl.2015.01.019 BindingDB Entry DOI: 10.7270/Q2GB25SJ | |||||||||||
More data for this Ligand-Target Pair |