BDBM50101853 (11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en-1-oic acid::(13E,15S)-11alpha,15-dihydroxy-9-oxoprost-13-en-1-oic acid::11alpha,15alpha-dihydroxy-9-oxo-13-trans-prostenoic acid::ALPROSTADIL::CHEMBL495::PGE-1::PGE1::prostaglandin E1
SMILES: CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O
InChI Key: InChIKey=GMVPRGQOIOIIMI-DWKJAMRDSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostanoid EP4 Receptor (Mus musculus (Mouse)) | BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Affinity for mouse Prostanoid EP4 receptor expressed in CHO cells | Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP4 receptor (Mus musculus (Mouse)) | BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Affinity for mouse Prostanoid EP4 receptor expressed in CHO cells | Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP4 Receptor (Mus musculus (Mouse)) | BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Binding affinity towards mouse Prostanoid EP4 receptor in CHO cells. | Bioorg Med Chem Lett 11: 2025-8 (2001) BindingDB Entry DOI: 10.7270/Q2CV4H1T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP4 receptor (Mus musculus (Mouse)) | BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Effective concentration which increases intracellular c-AMP production in mouse Prostanoid EP4 receptor | Bioorg Med Chem Lett 11: 2029-31 (2001) BindingDB Entry DOI: 10.7270/Q2833R9D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP3 Receptor (Mus musculus (Mouse)) | BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Evaluated for its competitive binding affinity towards mouse Prostanoid EP3 receptor in CHO cells expressing prostanoid receptor | Bioorg Med Chem Lett 11: 2029-31 (2001) BindingDB Entry DOI: 10.7270/Q2833R9D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP3 Receptor (Mus musculus (Mouse)) | BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Affinity for mouse Prostanoid EP3 receptor expressed in CHO cells | Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP3 receptor (Mus musculus (Mouse)) | BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Affinity for mouse Prostanoid EP4 receptor expressed in CHO cells | Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP3 Receptor (Mus musculus (Mouse)) | BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Binding affinity towards mouse Prostanoid EP3 receptor in CHO cells. | Bioorg Med Chem Lett 11: 2025-8 (2001) BindingDB Entry DOI: 10.7270/Q2CV4H1T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP1 Receptor (Mus musculus (Mouse)) | BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Affinity for mouse Prostanoid EP1 receptor expressed in CHO cells | Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP2 Receptor (Mus musculus (Mouse)) | BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Affinity for mouse Prostanoid EP2 receptor expressed in CHO cells | Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP1 Receptor (Mus musculus (Mouse)) | BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Evaluated for its competitive binding affinity towards mouse Prostanoid EP1 receptor in CHO cells expressing prostanoid receptor | Bioorg Med Chem Lett 11: 2029-31 (2001) BindingDB Entry DOI: 10.7270/Q2833R9D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP1 receptor (Mus musculus (Mouse)) | BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Affinity for mouse Prostanoid EP4 receptor expressed in CHO cells | Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP2 Receptor (Mus musculus (Mouse)) | BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | 41 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Evaluated for its competitive binding affinity towards mouse Prostanoid EP2 receptor in CHO cells expressing prostanoid receptor | Bioorg Med Chem Lett 11: 2029-31 (2001) BindingDB Entry DOI: 10.7270/Q2833R9D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP2 receptor (Mus musculus (Mouse)) | BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | 41 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Effective concentration for increased intracellular c-AMP production by mouse Prostanoid EP4 receptor | Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP2 Receptor (Mus musculus (Mouse)) | BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | 87 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Binding affinity towards mouse Prostanoid EP2 receptor expressed in CHO cells. | Bioorg Med Chem Lett 11: 2025-8 (2001) BindingDB Entry DOI: 10.7270/Q2CV4H1T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP1 Receptor (Mus musculus (Mouse)) | BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Binding affinity towards mouse Prostanoid EP1 receptor in CHO cells. | Bioorg Med Chem Lett 11: 2025-8 (2001) BindingDB Entry DOI: 10.7270/Q2CV4H1T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid IP receptor (Homo sapiens (Human)) | BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | 150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Affinity for mouse Prostanoid EP4 receptor expressed in CHO cells | Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid IP receptor (Homo sapiens (Human)) | BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | 150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Effective concentration which increases intracellular c-AMP production in mouse Prostanoid EP2 receptor | Bioorg Med Chem Lett 11: 2025-8 (2001) BindingDB Entry DOI: 10.7270/Q2CV4H1T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid IP receptor (Homo sapiens (Human)) | BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | 150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Evaluated for its competitive binding affinity towards human Prostanoid IP receptor in CHO cells | Bioorg Med Chem Lett 11: 2029-31 (2001) BindingDB Entry DOI: 10.7270/Q2833R9D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid IP receptor (Homo sapiens (Human)) | BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Affinity for human Prostanoid IP receptor expressed in CHO cells | Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP4 Receptor (Mus musculus (Mouse)) | BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Effective concentration which increases intracellular c-AMP production in mouse Prostanoid EP4 receptor | Bioorg Med Chem Lett 11: 2029-31 (2001) BindingDB Entry DOI: 10.7270/Q2833R9D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Multidrug resistance-associated protein 4 (Homo sapiens (Human)) | BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc Curated by ChEMBL | Assay Description Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and... | Toxicol Sci 136: 216-41 (2013) BindingDB Entry DOI: 10.7270/Q2JM2D2D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP4 receptor (Mus musculus (Mouse)) | BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Affinity for mouse Prostanoid EP4 receptor expressed in CHO cells | Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Canalicular multispecific organic anion transporter 2 (Homo sapiens (Human)) | BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 2.69E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc Curated by ChEMBL | Assay Description Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ... | Toxicol Sci 136: 216-41 (2013) BindingDB Entry DOI: 10.7270/Q2JM2D2D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier organic anion transporter family member 2B1 (Rattus norvegicus) | BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) | MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku University School of Medicine Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of PGD2 uptake in Xenopus laevis oocytes | Biochem Biophys Res Commun 275: 831-8 (2000) Article DOI: 10.1006/bbrc.2000.3377 BindingDB Entry DOI: 10.7270/Q2DN46J2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP4 receptor (Mus musculus (Mouse)) | BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 3.60 | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Affinity for mouse Prostanoid EP1 receptor expressed in CHO cells | Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid IP receptor (Homo sapiens (Human)) | BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | Article | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]-iloprost from Prostaglandin I2 receptor of human platelets | Bioorg Med Chem Lett 5: 1071-1076 (1995) Article DOI: 10.1016/0960-894X(95)00168-S BindingDB Entry DOI: 10.7270/Q29P31MX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Canalicular multispecific organic anion transporter 1 (Homo sapiens (Human)) | BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 1.33E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc Curated by ChEMBL | Assay Description Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and... | Toxicol Sci 136: 216-41 (2013) BindingDB Entry DOI: 10.7270/Q2JM2D2D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bile salt export pump (Homo sapiens (Human)) | BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 1.33E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc Curated by ChEMBL | Assay Description Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ... | Toxicol Sci 136: 216-41 (2013) BindingDB Entry DOI: 10.7270/Q2JM2D2D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid IP receptor (Homo sapiens (Human)) | BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Effective concentration which increases intracellular c-AMP production in human Prostanoid IP receptor | Bioorg Med Chem Lett 11: 2025-8 (2001) BindingDB Entry DOI: 10.7270/Q2CV4H1T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP2 receptor (Mus musculus (Mouse)) | BDBM50101853 ((11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Effective concentration which increases intracellular c-AMP production in mouse Prostanoid EP2 receptor | Bioorg Med Chem Lett 11: 2025-8 (2001) BindingDB Entry DOI: 10.7270/Q2CV4H1T | |||||||||||
More data for this Ligand-Target Pair |