BDBM50101864 4-(2-{(1R,2R,3R)-3-Hydroxy-2-[(E)-(S)-3-hydroxy-4-(4-hydroxy-3-methyl-phenyl)-but-1-enyl]-5-oxo-cyclopentyl}-ethylsulfanyl)-butyric acid::CHEMBL293647

SMILES: Cc1cc(C[C@H](O)\C=C\[C@H]2[C@H](O)CC(=O)[C@@H]2CCSCCCC(O)=O)ccc1O

InChI Key: InChIKey=KZNUTTVPLNHFID-ZVAONMGWSA-N

Data: 5 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50101864   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostanoid EP4 receptor (Mus musculus (Mouse))	BDBM50101864 (4-(2-{(1R,2R,3R)-3-Hydroxy-2-[(E)-(S)-3-hydroxy-4-...) Show SMILES Cc1cc(C[C@H](O)\C=C\[C@H]2[C@H](O)CC(=O)[C@@H]2CCSCCCC(O)=O)ccc1O Show InChI InChI=1S/C22H30O6S/c1-14-11-15(4-7-19(14)24)12-16(23)5-6-17-18(21(26)13-20(17)25)8-10-29-9-2-3-22(27)28/h4-7,11,16-18,20,23-25H,2-3,8-10,12-13H2,1H3,(H,27,28)/b6-5+/t16-,17-,18-,20-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Affinity for mouse Prostanoid EP4 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostanoid EP3 Receptor (Mus musculus (Mouse))	BDBM50101864 (4-(2-{(1R,2R,3R)-3-Hydroxy-2-[(E)-(S)-3-hydroxy-4-...) Show SMILES Cc1cc(C[C@H](O)\C=C\[C@H]2[C@H](O)CC(=O)[C@@H]2CCSCCCC(O)=O)ccc1O Show InChI InChI=1S/C22H30O6S/c1-14-11-15(4-7-19(14)24)12-16(23)5-6-17-18(21(26)13-20(17)25)8-10-29-9-2-3-22(27)28/h4-7,11,16-18,20,23-25H,2-3,8-10,12-13H2,1H3,(H,27,28)/b6-5+/t16-,17-,18-,20-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Affinity for mouse Prostanoid EP3 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostanoid EP2 Receptor (Mus musculus (Mouse))	BDBM50101864 (4-(2-{(1R,2R,3R)-3-Hydroxy-2-[(E)-(S)-3-hydroxy-4-...) Show SMILES Cc1cc(C[C@H](O)\C=C\[C@H]2[C@H](O)CC(=O)[C@@H]2CCSCCCC(O)=O)ccc1O Show InChI InChI=1S/C22H30O6S/c1-14-11-15(4-7-19(14)24)12-16(23)5-6-17-18(21(26)13-20(17)25)8-10-29-9-2-3-22(27)28/h4-7,11,16-18,20,23-25H,2-3,8-10,12-13H2,1H3,(H,27,28)/b6-5+/t16-,17-,18-,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	7.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Affinity for mouse Prostanoid EP2 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostanoid EP1 Receptor (Mus musculus (Mouse))	BDBM50101864 (4-(2-{(1R,2R,3R)-3-Hydroxy-2-[(E)-(S)-3-hydroxy-4-...) Show SMILES Cc1cc(C[C@H](O)\C=C\[C@H]2[C@H](O)CC(=O)[C@@H]2CCSCCCC(O)=O)ccc1O Show InChI InChI=1S/C22H30O6S/c1-14-11-15(4-7-19(14)24)12-16(23)5-6-17-18(21(26)13-20(17)25)8-10-29-9-2-3-22(27)28/h4-7,11,16-18,20,23-25H,2-3,8-10,12-13H2,1H3,(H,27,28)/b6-5+/t16-,17-,18-,20-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Affinity for mouse Prostanoid EP1 receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostanoid IP receptor (Homo sapiens (Human))	BDBM50101864 (4-(2-{(1R,2R,3R)-3-Hydroxy-2-[(E)-(S)-3-hydroxy-4-...) Show SMILES Cc1cc(C[C@H](O)\C=C\[C@H]2[C@H](O)CC(=O)[C@@H]2CCSCCCC(O)=O)ccc1O Show InChI InChI=1S/C22H30O6S/c1-14-11-15(4-7-19(14)24)12-16(23)5-6-17-18(21(26)13-20(17)25)8-10-29-9-2-3-22(27)28/h4-7,11,16-18,20,23-25H,2-3,8-10,12-13H2,1H3,(H,27,28)/b6-5+/t16-,17-,18-,20-/m1/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Affinity for human Prostanoid IP receptor expressed in CHO cells				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair
Prostanoid EP4 Receptor (Mus musculus (Mouse))	BDBM50101864 (4-(2-{(1R,2R,3R)-3-Hydroxy-2-[(E)-(S)-3-hydroxy-4-...) Show SMILES Cc1cc(C[C@H](O)\C=C\[C@H]2[C@H](O)CC(=O)[C@@H]2CCSCCCC(O)=O)ccc1O Show InChI InChI=1S/C22H30O6S/c1-14-11-15(4-7-19(14)24)12-16(23)5-6-17-18(21(26)13-20(17)25)8-10-29-9-2-3-22(27)28/h4-7,11,16-18,20,23-25H,2-3,8-10,12-13H2,1H3,(H,27,28)/b6-5+/t16-,17-,18-,20-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Effective concentration for increased intracellular c-AMP production by mouse Prostanoid EP4 receptor				Bioorg Med Chem Lett 11: 2033-5 (2001) BindingDB Entry DOI: 10.7270/Q24B30K2
					More data for this Ligand-Target Pair