BDBM50102093 (6,7-Dimethoxy-quinazolin-4-yl)-m-tolyl-amine::6,7-dimethoxy-N-m-tolylquinazolin-4-amine::CHEMBL56802

SMILES: COc1cc2ncnc(Nc3cccc(C)c3)c2cc1OC

InChI Key: InChIKey=RSVNNWQHWIOIOC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50102093   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50102093 ((6,7-Dimethoxy-quinazolin-4-yl)-m-tolyl-amine | 6,...) Show SMILES COc1cc2ncnc(Nc3cccc(C)c3)c2cc1OC Show InChI InChI=1S/C17H17N3O2/c1-11-5-4-6-12(7-11)20-17-13-8-15(21-2)16(22-3)9-14(13)18-10-19-17/h4-10H,1-3H3,(H,18,19,20)	PDB MMDB KEGG B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description In vitro inhibitory activity against Epidermal growth factor receptor (EGFR-TK) from A431 vulval squamous carcinoma cells using TKI assay				Bioorg Med Chem Lett 11: 1911-4 (2001) BindingDB Entry DOI: 10.7270/Q2XD1261
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50102093 ((6,7-Dimethoxy-quinazolin-4-yl)-m-tolyl-amine | 6,...) Show SMILES COc1cc2ncnc(Nc3cccc(C)c3)c2cc1OC Show InChI InChI=1S/C17H17N3O2/c1-11-5-4-6-12(7-11)20-17-13-8-15(21-2)16(22-3)9-14(13)18-10-19-17/h4-10H,1-3H3,(H,18,19,20)	PDB MMDB KEGG B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of human recombinant EGFR				J Med Chem 52: 964-75 (2009) Article DOI: 10.1021/jm800829v BindingDB Entry DOI: 10.7270/Q27W6C7Q
					More data for this Ligand-Target Pair