BindingDB logo
myBDB logout

null

SMILES: [O-][n+]1cc(ccc1Cl)C(=O)NCc1ccc(F)cc1

InChI Key: InChIKey=PVKNFEVXYDPTDR-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50102214   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-X-C chemokine receptor type 2


(Homo sapiens (Human))		BDBM50102214
PNG
(6-Chloro-N-(4-fluoro-benzyl)-1-oxy-nicotinamide | ...)
Show SMILES [O-][n+]1cc(ccc1Cl)C(=O)NCc1ccc(F)cc1
Show InChI InChI=1S/C13H10ClFN2O2/c14-12-6-3-10(8-17(12)19)13(18)16-7-9-1-4-11(15)5-2-9/h1-6,8H,7H2,(H,16,18)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



Celltech R&D

Curated by ChEMBL


Assay Description
Evaluated using an SPA assay with recombinant human [125I]-IL-8 and membranes preparedfrom Sf9 cells expressing human CXCR2

Bioorg Med Chem Lett 11: 1951-4 (2001)


BindingDB Entry DOI: 10.7270/Q2TX3DN0
More data for this
Ligand-Target Pair