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SMILES: OC(=O)c1cccc(c1)S(=O)(=O)c1ccc(c[n+]1[O-])C(=O)Nc1ccc(F)cc1

InChI Key: InChIKey=AFLYDJQMACMKQP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50102217   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-X-C chemokine receptor type 2


(Homo sapiens (Human))		BDBM50102217
PNG
(3-[5-(4-Fluoro-phenylcarbamoyl)-1-oxy-pyridine-2-s...)
Show SMILES OC(=O)c1cccc(c1)S(=O)(=O)c1ccc(c[n+]1[O-])C(=O)Nc1ccc(F)cc1
Show InChI InChI=1S/C19H13FN2O6S/c20-14-5-7-15(8-6-14)21-18(23)13-4-9-17(22(26)11-13)29(27,28)16-3-1-2-12(10-16)19(24)25/h1-11H,(H,21,23)(H,24,25)
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PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 32n/an/an/an/an/an/a



Celltech R&D

Curated by ChEMBL


Assay Description
Evaluated using an SPA assay with recombinant human [125I]-IL-8 and membranes preparedfrom Sf9 cells expressing human CXCR2

Bioorg Med Chem Lett 11: 1951-4 (2001)


BindingDB Entry DOI: 10.7270/Q2TX3DN0
More data for this
Ligand-Target Pair