BDBM50102301 4-[4-Formyl-5-hydroxy-6-methyl-3-(2-phosphono-ethyl)-pyridin-2-ylazo]-benzoic acid::CHEMBL117766
SMILES: Cc1nc(N=Nc2ccc(cc2)C(O)=O)c(CCP(O)(O)=O)c(C=O)c1O
InChI Key: InChIKey=YUTIZIKCXZOYSN-UHFFFAOYSA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
P2Y purinoceptor 1 (Meleagris gallopavo) | BDBM50102301 (4-[4-Formyl-5-hydroxy-6-methyl-3-(2-phosphono-ethy...) | MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Inhibition of 10 nM 2-MeSADP-stimulated phospholipase C in turkey erythrocyte membranes using [3H]-inositol | J Med Chem 44: 340-9 (2001) BindingDB Entry DOI: 10.7270/Q2FN15HC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2X purinoceptor 1 (RAT) | BDBM50102301 (4-[4-Formyl-5-hydroxy-6-methyl-3-(2-phosphono-ethy...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Inhibition of inward ion current elicited by ATP at P2X1 receptor expressed in Xenopus oocytes | J Med Chem 44: 340-9 (2001) BindingDB Entry DOI: 10.7270/Q2FN15HC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2X purinoceptor 3 (RAT) | BDBM50102301 (4-[4-Formyl-5-hydroxy-6-methyl-3-(2-phosphono-ethy...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 145 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Inhibition of inward ion current elicited by ATP was determined at recombinant P2X3 receptor expressed in Xenopus oocytes | J Med Chem 44: 340-9 (2001) BindingDB Entry DOI: 10.7270/Q2FN15HC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Purinergic, P2X2 (RAT) | BDBM50102301 (4-[4-Formyl-5-hydroxy-6-methyl-3-(2-phosphono-ethy...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Inhibition of inward ion current elicited by ATP at P2X2 receptor expressed in Xenopus oocytes | J Med Chem 44: 340-9 (2001) BindingDB Entry DOI: 10.7270/Q2FN15HC | |||||||||||
More data for this Ligand-Target Pair |