BDBM50102688 4-Benzyloxy-N-(1-dimethylamino-cyclohexylmethyl)-3,5-dimethoxy-benzamide::CHEMBL92310

SMILES: COc1cc(cc(OC)c1OCc1ccccc1)C(=O)NCC1(CCCCC1)N(C)C

InChI Key: InChIKey=LZUPBAJBKIDDAG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50102688   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycine transporter 2 (Homo sapiens (Human))	BDBM50102688 (4-Benzyloxy-N-(1-dimethylamino-cyclohexylmethyl)-3...) Show SMILES COc1cc(cc(OC)c1OCc1ccccc1)C(=O)NCC1(CCCCC1)N(C)C Show InChI InChI=1S/C25H34N2O4/c1-27(2)25(13-9-6-10-14-25)18-26-24(28)20-15-21(29-3)23(22(16-20)30-4)31-17-19-11-7-5-8-12-19/h5,7-8,11-12,15-16H,6,9-10,13-14,17-18H2,1-4H3,(H,26,28)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd. Curated by ChEMBL					Assay Description Inhibition of human Glycine Transporter type-2				J Med Chem 44: 2679-82 (2001) BindingDB Entry DOI: 10.7270/Q2DN44BJ
					More data for this Ligand-Target Pair
Glycine transporter 1 (Homo sapiens (Human))	BDBM50102688 (4-Benzyloxy-N-(1-dimethylamino-cyclohexylmethyl)-3...) Show SMILES COc1cc(cc(OC)c1OCc1ccccc1)C(=O)NCC1(CCCCC1)N(C)C Show InChI InChI=1S/C25H34N2O4/c1-27(2)25(13-9-6-10-14-25)18-26-24(28)20-15-21(29-3)23(22(16-20)30-4)31-17-19-11-7-5-8-12-19/h5,7-8,11-12,15-16H,6,9-10,13-14,17-18H2,1-4H3,(H,26,28)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
Organon Laboratories Ltd. Curated by ChEMBL					Assay Description In vitro inhibition of human Glycine Transporter type-1.				J Med Chem 44: 2679-82 (2001) BindingDB Entry DOI: 10.7270/Q2DN44BJ
					More data for this Ligand-Target Pair